Results 111 to 120 of about 1,477,728 (279)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

3DMADMAC|AUTOMATED: synergistic hardware and software solution for automated 3D digitization of cultural heritage objects

open access: yesGeoinformatics FCE CTU, 2011
In this article a fully automated 3D shape measurement system and data processing algorithms are presented. Main purpose of this system is to automatically (without any user intervention) and rapidly (at least ten times faster than manual measurement ...
Robert Sitnik   +3 more
doaj   +1 more source

Fusion of IRST and Radar Measurements for 3D Target Tracking [PDF]

open access: yes, 2009
Two different types of measurement fusion methods for fusing IRST (infrared search and track) and radar measurements to track a target in 3D Cartesian coordinates are evaluated and discussed in this paper.
Naidu, VPS
core  

Full field inversion in photoacoustic tomography with variable sound speed

open access: yes, 2018
Recently, a novel measurement setup has been introduced to photoacoustic tomography, that collects data in the form of projections of the full 3D acoustic pressure distribution at a certain time instant.
Haltmeier, Markus   +3 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Measuring Cubeness of 3D Shapes [PDF]

open access: yes, 2009
In this paper we introduce a new measure for 3D shapes: cubeness. The new measure ranges over [0,1] and reaches 1 only when the given shapes is a cube. The new measure is invariant with respect to rotation, translation and scaling, and is also robust with respect to noise.
Carlos Martinez-Ortiz, Joviša Žunić
openaire   +1 more source

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