Results 151 to 160 of about 1,477,728 (279)
Evaluation of measurement technique for a precision aspheric artefact using a nano-measuring machine [PDF]
A precision aspheric artefact is measured in 3D by a commercially available nano-measuring machine (NMM) integrated with a contact inductive sensor as the probe. The mathematics of 3D compensation of the error caused by the probe radius is derived.
Chen, Xiaomei +3 more
core
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Frontiers in MedicineObjectivesTo evaluate the reliability and accuracy of a portable structured light-based three-dimensional (3D) imaging system for volumetric measurement in the periorbital region.MethodsFive hemispherical 3D printed resin models with different sizes and ...
Xuan Zhang +6 more
doaj +1 more source
Magnetic Resonance 3D Measurement of the Endolymphatic Space in 100 Control Human Subjects. [PDF]
J Int Adv Otol, 2021 Inui H, Kitahara T, Ito T, Sakamoto T.
europepmc +1 more source
Motion studies of high current arcs using an optical fibre array imaging system
, 2009 This paper presents an integrated portable measurement system for thestudy of high speed and high temperature unsteady plasma flows such as thosefound in the vicinity of high current switching arcs.
Cross, K. +3 more
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Uniaxial 3D Measurement with Auto-Synchronous Phase-Shifting and Defocusing Based on a Tilted Grating. [PDF]
Sensors (Basel), 2021 Ren H, Liu Y, Wang Y, Liu N, Yu X, Su X.
europepmc +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source