Results 61 to 70 of about 315,050 (269)

Interoperability of photogrammetry in 3D modeling: documentation, research and dissemination in the archaeological site of Jamila

open access: yesVirtual Archaeology Review, 2015
This paper intends to be a sample, both theoretical and practical, of a protocol for the use of photogrammetric resources when generating a three-dimensional archaeological model.
Pedro R. Moya-Maleno   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Large-Scale Urban 3D Geological Modeling Based on Multi-Method Coupling Under Multi-Source Heterogeneous Data Conditions

open access: yesApplied Sciences
The development and utilization of urban underground space represents a crucial strategy for achieving sustainable urban development. Three-dimensional (3D) geological models provide a data foundation and technical support for research in urban planning ...
Jixiang Zhu   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

THREE DIMENSIONAL PRINTING TECHNOLOGY IN THE EDUCATIONAL PROCESS FOR THE DISCIPLINE «ENGINEERING GRAPHICS»

open access: yesСовременная наука и инновации, 2022
The article provides an overview of additive technologies for SD printing. An example of the introduction and use of SD printing technologies in the educational process for the discipline «engineering graphics».
Sergey Evgen'evitch Abramkin   +1 more
doaj  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Digitization and Preservation of Natural Heritage Supported by Digital Fabrication Technologies

open access: yesUniciencia
[Objective] This study aimed to implement 3D image acquisition and postprocessing tools for the natural heritage preservation of a collection of craniums from a zoology museum and a wildlife rescue center.
Luis David Badilla Oviedo   +5 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

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