Results 211 to 220 of about 2,985,578 (313)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

A 3D lymph node model for chronic lymphocytic leukaemia recapitulates microenvironmental features and drug response in vitro

Disease Models & Mechanisms
Daniela Belloni, Dafne Barozzi, Giulia Milani, Federica Barbaglio, Aswin Raj Puthukkunnath, Pamela Ranghetti, Eleonora Perotta, Teresa Musco, Marta Sampietro, Maurilio Ponzoni, Lydia Scarfò, Paolo Ghia, Cristina Scielzo   +12 more
doaj   +1 more source

Two-Step Parametrial Endometriosis Nodule Excision Using Virtual Reality Technology and 3D Modelling for Surgical Planning. [PDF]

Case Rep Obstet Gynecol
Sinha R, Singh S, Flaxman T.
europepmc   +1 more source

From a Point Cloud to a Simulation Model-Bayesian Segmentation and Entropy Based Uncertainty Estimation for 3D Modelling. [PDF]

Entropy (Basel), 2021
Petschnigg C, Spitzner M, Weitzendorf L, Pilz J.   +3 more
europepmc   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Quantifying the effects of far-red light on lettuce photosynthesis and growth using a 3D modelling approach. [PDF]

Front Plant Sci
Li J, Li Y, Chen Y, Xu S, Wu X, Wu C, Zhang N, Cao K.   +7 more
europepmc   +1 more source

Mycorrhizal associations change root functionality: a 3D modelling study on competitive interactions between plants for light and nutrients. [PDF]

New Phytol, 2021
de Vries J, Evers JB, Kuyper TW, van Ruijven J, Mommer L.   +4 more
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

High-fidelity 3D modelling of the lumbar dorsal rami. [PDF]

Interv Pain Med
Tran J, Campisi E, Roa Agudelo A, Agur AM, Loh E.   +4 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source