Results 61 to 70 of about 87,444 (266)
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Spatial ETL for 3D Building Modelling Based on Unmanned Aerial Vehicle Data in Semi-Urban Areas
Remote Sensing, 2020 This paper provides the innovative approach of using a spatial extract, transform, load (ETL) solution for 3D building modelling, based on an unmanned aerial vehicle (UAV) photogrammetric point cloud.
Urška Drešček +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
ACCURACY RESEARCH OF THE EFFECT OF LOCAL SURFACE MODELING METHODS ON THE GENERATION OF 3D MODELS OF HISTORICAL OBJECTS WITH ROCK-BASED BUILDING STRUCTURES USING OPEN-SOURCE SOFTWARE [PDF]
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information SciencesThe paper describes the effect of the local surface modelling methods known as plane, quadric and triangulation on the generation of the 3D mesh models of the historical objects with rock-based building structures using Cloudcompare, an open-source ...
Z. Majid +7 more
doaj +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
GeoPDNN 1.0: a semi-supervised deep learning neural network using pseudo-labels for three-dimensional shallow strata modelling and uncertainty analysis in urban areas from borehole data [PDF]
Geoscientific Model DevelopmentBorehole data are essential for conducting precise urban geological surveys and large-scale geological investigations. Traditionally, explicit modelling and implicit modelling have been the primary methods for visualizing borehole data and constructing ...
J. Guo +12 more
doaj +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
آموزش مهندسی ایران, 2017 The necessity of teaching 3D computer modelling to engineering students is studied in this paper. Firstly, the applications of 3D computer modelling in engineering design are described and then an investigation is carried out to understand how it can ...
Alireza jahantigh, Mohammad Ali Daeian
doaj +1 more source
3D Face Modeling based on 3D Morphable Shape Model
The Journal of the Korea Contents Association, 2008 Since 3D face can be rotated freely in 3D space and illumination effects can be modeled properly, 3D face modeling Is more precise and realistic in face pose, illumination, and expression than 2D face modeling. Thus, 3D modeling is necessitated much in face recognition, game, avatar, and etc. In this paper, we propose a 3D face modeling method based on
Yong-Suk Jang +3 more
openaire +2 more sources
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source