Results 71 to 80 of about 660,620 (286)
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
How realistic are solar model atmospheres? [PDF]
, 2013 Recently, new solar model atmospheres have been developed to replace classical 1D LTE hydrostatic models and used to for example derive the solar chemical composition. We aim to test various models against key observational constraints.
Asplund, Martin +5 more
core +2 more sources
3D Modelling and Printing Technology to Produce Patient-Specific 3D Models [PDF]
Heart, Lung and Circulation, 2019 A comprehensive knowledge of mitral valve (MV) anatomy is crucial in the assessment of MV disease. While the use of three-dimensional (3D) modelling and printing in MV assessment has undergone early clinical evaluation, the precision and usefulness of this technology requires further investigation.
Nicolette S, Birbara +2 more
openaire +2 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
3D modelling of geological and anthropogenic deposits at the World Heritage Site of Bryggen in Bergen, Norway [PDF]
, 2012 The landscape of many historic cities and the character of their shallow subsurface environments are defined by a legacy of interaction between anthropogenic and geological processes. Anthropogenic deposits and excavations result from processes ranging
Caple +37 more
core +1 more source
Th sensitivity of 3D separations in multi-stage compressors
Journal of the Global Power and Propulsion Society, 2018 One of the most important questions facing a compressor designer is how accurately their computational code predicts the size of 3D corner separations. This is because the size of the 3D corner separation sets the compressors off-design performance and ...
Kiran Auchoybur, Robert Miller
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
TVL1shape approximation from scattered 3D data [PDF]
, 2015 With the emergence in 3D sensors such as laser scanners and 3D reconstruction from cameras, large 3D point clouds can now be sampled from physical objects within a scene.
Boerner, A., Dooley, L. S., Funk, E.
core
, 2017 While deep convolutional neural networks (CNN) have been successfully applied for 2D image analysis, it is still challenging to apply them to 3D anisotropic volumes, especially when the within-slice resolution is much higher than the between-slice ...
Cai, Weidong +9 more
core +1 more source