Results 71 to 80 of about 28,123,411 (300)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

3D sensing of back symmetry curve suited for dynamic analysis of spinal deformities

Automatika, 2018
This paper is focused on meeting the demands for better detection and evaluation of the spinal deformities that go beyond a basic static 3D analysis.
Matea Ðonlić, Tomislav Petković, Stanislav Peharec, Tomislav Pribanić   +3 more
doaj   +1 more source

Diving performance analysis with 3D motion knowledge hypergraphs

Multimedia Systems
Abstract Diving actions involve complex temporal dynamics, rapid pose transitions, and strict requirements for entry angles and splash control, making quality assessment a challenging task in computer vision. Existing methods still face limitations in motion structure modeling, depth perception, and multimodal fusion.
Jingbo Wang, Yifan Xie, Yitao Xie, Hongyu Xiao   +3 more
openaire   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Description of marker locations used for the 3D-Motion analysis.

, 2022
Description of marker locations used for the 3D-Motion analysis.
Bjoern Braunstein (6330926), Tobias Weber (6330914), James Cowburn (14165084), Dario Cazzola (3615779), Gaspare Pavei (3631405), David A. Green (7851419), Nolan Herssens (5470409), Jörn Rittweger (485601), Steffi Colyer (13809795), Alberto E. Minetti (9128324), Kirsten Albracht (3754045)   +10 more
core   +1 more source

Automatic reconstruction of 3D human arm motion from a monocular image sequence [PDF]

, 1998
A model-based approach to reconstruction of 3D human arm motion from a monocular image sequence taken under orthographic projection is presented. The reconstruction is divided into two stages.
Solina, Franc, Filova, Valentina, Lenarčič, Jadran   +2 more
core   +1 more source

Computer-Assisted Reconstruction and Motion Analysis of the Three-Dimensional Cell

The Scientific World Journal, 2003
Even though several microscopic techniques provide three-dimensional (3D) information on fixed and living cells, the perception persists that cells are two-dimensional (2D). Cells are, in fact, 3D and their behavior, including the extension of pseudopods,
David R. Soll, Deborah Wessels, Paul J. Heid, Edward Voss   +3 more
doaj   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Multiple description video coding for stereoscopic 3D [PDF]

, 2009
In this paper, we propose an MDC schemes for stereoscopic 3D video. In the literature, MDC has previously been applied in 2D video but not so much in 3D video.
Worrall, S, Sali, Aduwati, Kondoz, AM, Sadka, AH, Worral, S., Abdul Karim, H, Sadka, A. H., Kondoz, A. M., Karim, H., Sali, A, Karim, HA   +10 more
core   +1 more source