Results 41 to 50 of about 3,277,616 (304)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Veterinary Students’ Assessment of 3D Anatomical Prints as New Teaching Material in Practical Veterinary Anatomy Classes

Education Sciences
This work aims to evaluate students’ opinions on the materials normally used in anatomy practical classes (fixed and plastinated) compared to 3D anatomical prints.
Elena Díaz Martínez, Gregorio J. Ramírez Zarzosa, Alberto Arencibia Espinosa, Marta Soler Laguía, Daniel Rojo Rios, Ainara Ortuño Lorente, María Leotte Sánchez, Diana Ceballos-Francisco, María Inmaculada García García, Francisco Gil Cano, David Kilroy, Francisco Martínez Gomariz, Cayetano Sánchez Collado, María Dolores Ayala Florenciano   +13 more
doaj   +1 more source

3D-printed bioanalytical devices [PDF]

Nanotechnology, 2016
While 3D printing technologies first appeared in the 1980s, prohibitive costs, limited materials, and the relatively small number of commercially available printers confined applications mainly to prototyping for manufacturing purposes. As technologies, printer cost, materials, and accessibility continue to improve, 3D printing has found widespread ...
Bishop, Gregory W., Satterwhite-Warden, Jennifer E., Kadimisetty, Karteek, Rusling, James F.   +3 more
openaire   +4 more sources

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Identifying a commercially-available 3D printing process that minimizes model distortion after annealing and autoclaving and the effect of steam sterilization on mechanical strength

3D Printing in Medicine, 2020
Background Fused deposition modeling 3D printing is used in medicine for diverse purposes such as creating patient-specific anatomical models and surgical instruments.
Joshua V. Chen, Kara S. Tanaka, Alan B. C. Dang, Alexis Dang   +3 more
doaj   +1 more source

Simultaneous non-contact identification of the elastic modulus, damping and coefficient of thermal expansion in 3D-printed structures

Polymer Testing, 2023
Thermoplastic-extrusion 3D printing has gained popularity for the fabrication of electrothermal soft actuators that can control shape in response to temperature changes generated by embedded 3D-printed heaters.
Gašper Krivic, Janko Slavič
doaj   +1 more source

3D‐Printed Artificial Microfish [PDF]

Advanced Materials, 2015
Hydrogel microfish featuring biomimetic structures, locomotive capabilities, and functionalized nanoparticles are engineered using a rapid 3D printing platform: microscale continuous -optical printing (μCOP). The 3D-printed -microfish exhibit chemically powered and magnetically guided propulsion, as well as highly efficient detoxification capabilities ...
Zhu, Wei, Li, Jinxing, Leong, Yew J., Rozen, Isaac, Qu, Xin, Dong, Renfeng, Wu, Zhiguang, Gao, Wei, Chung, Peter H., Wang, Joseph, Chen, Shaochen   +10 more
openaire   +4 more sources