Results 41 to 50 of about 460,480 (261)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

3D Model Identification Using Weighted Implicit Shape Representation and Panoramic View

Applied Sciences, 2017
In this paper, we propose a 3 dimensional (3D) model identification method based on weighted implicit shape representation (WISR) and panoramic view. The WISR is used for 3D shape normalization.
Xun Jin, Jongweon Kim
doaj   +1 more source

Text‐to‐3D Shape Generation

Computer Graphics Forum
AbstractRecent years have seen an explosion of work and interest in text‐to‐3D shape generation. Much of the progress is driven by advances in 3D representations, large‐scale pretraining and representation learning for text and image data enabling generative AI models, and differentiable rendering.
Han-Hung Lee, Manolis Savva, Angel X. Chang   +2 more
openaire   +2 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Modeling 3D facial shape from DNA. [PDF]

PLoS Genetics, 2014
Human facial diversity is substantial, complex, and largely scientifically unexplained. We used spatially dense quasi-landmarks to measure face shape in population samples with mixed West African and European ancestry from three locations (United States,
Peter Claes, Denise K Liberton, Katleen Daniels, Kerri Matthes Rosana, Ellen E Quillen, Laurel N Pearson, Brian McEvoy, Marc Bauchet, Arslan A Zaidi, Wei Yao, Hua Tang, Gregory S Barsh, Devin M Absher, David A Puts, Jorge Rocha, Sandra Beleza, Rinaldo W Pereira, Gareth Baynam, Paul Suetens, Dirk Vandermeulen, Jennifer K Wagner, James S Boster, Mark D Shriver   +22 more
doaj   +1 more source

Inconsistency of perceived 3D shape

Vision Research, 2010
Internal consistency of local depth, slant, and curvature judgments was studied by asking participants to match two 3D surfaces rendered by different mixtures of 3D cues (velocity, texture, and shading). We found that perceptual judgments were not consistent with each other, with cue-specific distortions.
M. Di Luca, F. Domini, CAUDEK, CORRADO
openaire   +4 more sources

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source