Results 51 to 60 of about 176,543 (244)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Measuring perceived 3D shape at multiple spatial scales

Vision Research, 1999
We present and test a novel multiscale representation of perceived 3D surface orientation: the orientation path. Using a multiscale probe, we measure perceived surface orientation at multiple spatial scales: linking the measurements for a given surface location yields that location's orientation path.
Brown, Peter H, Burbeck, Christina A
openaire   +2 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

3D reconstruction from structured-light profilometry with dual-path hybrid network

EURASIP Journal on Advances in Signal Processing, 2022
With the rapid development of high-speed image sensors and optical imaging technology, these have effectively promoted the improvement of non-contact 3D shape measurement.
Lei Wang, Dunqiang Lu, Ruowen Qiu, Jiaqing Tao   +3 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

High-speed 3D shape measurement using Fourier transform and stereo vision

Journal of the European Optical Society-Rapid Publications, 2018
Background In the fast 3D shape measurement, it is an important factor to use the least number of fringe patterns to get the wrapped phase and the wrapped phase is always required to be retrieved to absolute phase. But the process of phase unwrapping may
Feng Lu, Chengdong Wu, Jikun Yang
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

3D-Shape Measurement Based on Defocus Characteristic

IEEJ Transactions on Electronics, Information and Systems, 2009
Measurement and reconstruction of 3-dimensional scenes by a visual system is very important subject in the field of Computer Vision. In this article, we propose a method that estimates 3-dimensional structures by using only one input image obtained by a monocular camera. Blurring of image by defocus is a clue to estimating a relative range image, so we
Yuusuke Mochiduki, Kimiya Aoki, Hiroyasu Koshimizu   +2 more
openaire   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

3D shape measurement with thermal pattern projection

Advanced Optical Technologies, 2016
AbstractStructured light projection techniques are well-established optical methods for contactless and nondestructive three-dimensional (3D) measurements. Most systems operate in the visible wavelength range (VIS) due to commercially available projection and detection technology.
Anika Brahm, Edgar Reetz, Simon Schindwolf, Martin Correns, Peter Kühmstedt, Gunther Notni   +5 more
openaire   +1 more source