Results 71 to 80 of about 7,693,136 (320)

3D Neuro-electronic interface devices for neuromuscular control: Design studies and realisation steps [PDF]

, 1995
In order to design the shape and dimensions of new 3D multi-microelectrode information transducers properly, i. e. adapted to the scale of information delivery to and from peripheral nerve fibres, a number of studies were, and still are, being performed ...
Frieswijk, Theo A., Meier, Jan H., Rozijn, Tom H., Rutten, Wim L.C., Smit, Jos P.A.   +4 more
core   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Developing an anti-spastic orthosis for daily home-use of stroke patients using smart memory alloys and 3D printing technologies

Materials & Design, 2020
Spasticity is an important factor limiting independency and activity of daily living for post-stroke patients. Our aim was to develop a cost effective, customized, lightweight active orthosis, which is convenient for daily home use.The study describes ...
Luca Toth, Adam Schiffer, Miklos Nyitrai, Attila Pentek, Roland Told, Peter Maroti   +5 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Numerical investigation on natural convective heat transfer of Al2O3-water nanofluids (About the effect of thermophysical properties)

Nihon Kikai Gakkai ronbunshu, 2016
Nanofluids are suspension dispersed nano-scale particles in a base fluid. In this study, natural convective heat transfer characteristics of Al2O3-water nanofluids in a vertical cylindrical container heated from below and cooled from above are ...
Masato AKAMATSU, Takuto KAMEYAMA, Yuki YOMOGITA, Mitsuo IWAMOTO, Hiroyuki OZOE   +4 more
doaj   +1 more source

Research on Application of 3D Simulation Technology in Industrial Product Design Technology

Advances in Multimedia, 2022
In order to study the driving effect of industrial product design, a method based on the application of 3D simulation technology in industrial product design technology was proposed.
Chenhan Huang, Daijiao Shi
doaj   +1 more source

UT Austin Villa 2014: RoboCup 3D Simulation League Champion via Overlapping Layered Learning

AAAI Conference on Artificial Intelligence, 2015
Layered learning is a hierarchical machine learning paradigm that enables learning of complex behaviors by incrementally learning a series of sub-behaviors.
Patrick MacAlpine, Mike Depinet, P. Stone   +2 more
semanticscholar   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Conductor losses calculation in two-dimensional simulations of H-plane rectangular waveguides [PDF]

, 2019
This paper presents a novel numerical approach to simulate H-plane rectangular-waveguide microwave circuits considering a reduced quasi-2D simulation domain with benefits for computational cost and time.
Castorina, G., Celona, L., Mostacci, A., Sorbello, G., Torrisi, G.   +4 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source