4-Aminobenzoic Acid Derivatives: Converting Folate Precursor to Antimicrobial and Cytotoxic Agents [PDF]
4-aminobenzoic acid (PABA), an essential nutrient for many human pathogens, but dispensable for humans, and its derivatives have exhibited various biological activities. In this study, we combined two pharmacophores using a molecular hybridization approach: this vitamin-like molecule and various aromatic aldehydes, including salicylaldehydes and 5 ...
Martin Krátký+7 more
europepmc +5 more sources
Corrosion resistance of stainless steel covered by 4-aminobenzoic acid films [PDF]
Abstract The protective, anticorrosion properties of 4-aminobenzoic acid (4-ABA) films are evaluated in the paper. The 4-ABA films were electrodeposited on the surface of both X20Cr13 stainless steel and glassy carbon electrodes by galvanostatically and cyclic voltammetry methods.
Anna Pietrusiak+2 more
doaj +4 more sources
Crystal structure of 4-aminobenzoic acid-4-methylpyridine (1/1) [PDF]
The authors wish to acknowledge the SAIF, IIT, Madras, for the data collection.Peer ...
Chakkaravarthi, G.+4 more
core +12 more sources
Creation of a ternary complex between a crown ether, 4-aminobenzoic acid and 3,5-dinitrobenzoic acid [PDF]
YesThe creation of ternary multi-component crystals through the introduction of 18-crown-6 to direct the hydrogen-bonding motifs of the other molecular components was investigated for 3,5-dinitrobenzoic acid (3,5-dnba) with 4-aminobenzoic acid (4-aba ...
Boardman, N.D.+3 more
core +6 more sources
Highly Magnetizable Crosslinked Chloromethylated Polystyrene-Based Nanocomposite Beads for Selective Molecular Separation of 4‑Aminobenzoic Acid [PDF]
In this work, we describe the preparation and characterization of highly magnetizable chloromethylated polystyrene-based nanocomposite beads. For synthesis optimization, acid-resistant core–shelled maghemite (γ-Fe2O3) nanoparticles are coated with sodium
Fábio T. Costa+7 more
doaj +3 more sources
Dye Sensitized Solar Cells Based on Hydrazonoyl Synthetic Dyes [PDF]
A group of chemical sensitizers of two hydrazonoyl based derivatives were synthesized. These derivatives contain a good π system for efficient light absorption and oxide sensitization.
Abdel-Latif, Monzir S.+8 more
core +3 more sources
4-Aminobenzoic acid–quinoline (1/1) [PDF]
In the title 1:1 adduct, C9H7N·C7H7NO2, the carboxyl group is twisted at an angle of 5.42 (8) Å with respect to its attached benzene ring. In the crystal, the carboxylic acid molecule is linked to the quinoline molecule by an O—H...N hydrogen bond. The 4-aminobenzoic acid molecules are linked by N—H...O hydrogen bonds, forming sheets propagating in ...
S. Israel+3 more
openaire +3 more sources
Diversity‐Oriented Synthesis and Antibiofilm Evaluation of Furan‐2‐Carboxamides [PDF]
Navigating through the chemical space of antibiofilm agents! Furan‐2‐carboxamides inhibit the production of this extracellular shield in Pseudomonas aeruginosa by modulating the linkers and substituents of the central core. The discovery offers a solution to the metabolically unstable antibiofilm agents based on furanones, leading to the design of more
Ana C. Muñoz‐Estrada+4 more
wiley +2 more sources
Replacing a Cereblon Ligand by a DDB1 and CUL4 Associated Factor 11 (DCAF11) Recruiter Converts a Selective Histone Deacetylase 6 PROTAC into a Pan‐Degrader [PDF]
This study introduced DCAF11 as an E3 ligase for PROTAC‐mediated histone deacetylase (HDAC) degradation. By replacing cereblon with DCAF11 as recruited E3 ligase, a selective HDAC6 degrader (A6) was transformed into pan‐HDAC degraders. The lead compound, 1j (FF2039), potently degraded HDACs from classes I, IIa, and IIb, showing strong antiproliferative
Felix Feller+5 more
wiley +2 more sources
Experimental study and thermodynamic modeling of the solubility of 4-aminobenzoic acid in binary mixtures of solvents [PDF]
Selection of an appropriate solvent is of interest in the pharmaceutical industry. In some case, a mixture of solvents has a more solubility than the pure solvents.
Afshin Shakoor, Aliakbar Roosta
doaj +1 more source