Results 181 to 190 of about 29,450,134 (264)

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Using Tennessee youth hippology contest results as a needs assessment for 4-H horse project members and development of a train-the-trainer program for Tennessee extension agents. [PDF]

Transl Anim Sci
Main SC, Ivey JLZ, Strickland LG, Rhinehart JD, Sun X.   +4 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

50% body weight loading reduces stature increases and lumbar disc expansion from 4 h hyper-buoyancy floatation versus 15 min sitting upright. [PDF]

Exp Physiol
Marcos-Lorenzo D, Lysandrou C, Sudres L, Gil-Martinez A, Swanenburg J, Clark JE, Green DA.   +6 more
europepmc   +1 more source

4-H Crop Projects 2: Soybeans & Corn—Green and Growing

, 2004
Welcome to the 4-H Crop Project Guide. This guide is intended to help you learn the basics about crop production and careers related to crop production.
Levings, Judith, Creswell, John, Schwab, Denise   +2 more
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Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Utility of digital images captured after 4 h of incubation on a microbiology laboratory automation system in guiding the work-up of subcultures from positive blood cultures. [PDF]

J Clin Microbiol
Cintrón M, Clark B, Miranda E, Babady NE.   +3 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Post-coordination of Ru(ii) controlled regioselective B(4)-H acylmethylation of <i>o</i>-carboranes with sulfoxonium ylides. [PDF]

Chem Sci
Cao HJ, Li JX, Yan JH, Liu MX, Zhao Q, Zhang J, Zhang J, Yan H.   +7 more
europepmc   +1 more source

Kansas 4-H journal, v. 9, no. 4 (April 1963)

, 1963
Magazine published by the Kansas 4-H Foundation. Began in 1955. It focuses on the following areas: careers and education, camping, communication, community service, donor recognition, state recognition, recruiting, project selection, leaders and parents’

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