Results 241 to 250 of about 7,294,678 (325)

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

Beneficial Physiological and Metabolic Effects with Acute Intake of New Zealand Blackcurrant Extract during 4 h of Indoor Cycling in a Male Ironman Athlete: A Case Study. [PDF]

J Funct Morphol Kinesiol
Willems MET, Spurr TJ, Lacey J, Briggs AR.   +3 more
europepmc   +1 more source

Studies on the Syntheses of Hydrogenated Quinolines and Isoquinolines as Analgesics. XI. Synthesis of N-Methyl-6-aza-des-N-morphinan (2-Methyl-5, 10b-trimethylene-1, 2, 3, 4, 4a, 5, 6, 10b-octahydrobenzo [h] isoquinoline).

, 1957
Norio Sugimoto, Susumu Ohshiro, Hiroshi Kugita, Seiichi Saito   +3 more
openalex   +2 more sources

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

On the Volumetric Estimation of Al by means of H<SUB>3</SUB>PO<SUB>4</SUB>-NaOH Titration

, 1954
Takao Honjo
openalex   +2 more sources

Sammlung Vulgärlateinischer Texte, herausgegeben von W. Heraeus und H. Morf. 3. Proben aus dem sogenannten Mulomedicina Chironis (II. und III.) von Max Niedermann. M. 1.20. 4. Kleine Texte zum Alexanderroman, von F. Pfister. Mit einem Faksimile. M. 1.20. Heidelberg: Winter, 1910. [PDF]

, 1911
W. H. D. R.
openalex   +1 more source

Forestry for 4-H clubs

, 1941
Wilbur R. Mattoon, Erwin H. Shinn
openaire   +4 more sources

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Factors associated with performance of 4-H club volunteer leaders in New York State, 1946-48

, 1950
Robert Crowthers Clark
openalex   +2 more sources

Book Reviews : The Financial History of Massachusetts from the Organization of the Massachusetts Bay Company to the American Revolution. By CHAS. H. A. DOUGLAS, Ph D., Columbia College. Studies in History, Economics, and Public Law. Vol. i., No. 4. Pp 148. New York, 1892 [PDF]

, 1892
Carl C. Plehn
openalex   +1 more source