Results 51 to 60 of about 6,834,237 (231)

Shedding Light on the Pharmacological Interactions between μ-Opioid Analgesics and Angiotensin Receptor Modulators: A New Option for Treating Chronic Pain

Molecules, 2021
The current protocols for neuropathic pain management include µ-opioid receptor (MOR) analgesics alongside other drugs; however, there is debate on the effectiveness of opioids. Nevertheless, dose escalation is required to maintain their analgesia, which,
Kornél Király, Dávid Á. Karádi, Ferenc Zádor, Amir Mohammadzadeh, Anna Rita Galambos, Mihály Balogh, Pál Riba, Tamás Tábi, Zoltán S. Zádori, Éva Szökő, Susanna Fürst, Mahmoud Al-Khrasani   +11 more
doaj   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro, Freda Qi, Karen Colwill, Alina D. Dorogy, Ying Liu, Michelle Science, Anne‐Claude Gingras, James M. Rini, Sumit Gupta, Sarah Alexander, Shelly Bolotin, Tania H. Watts   +11 more
wiley   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Effectiveness Regarding Hantavirus Detection in Rodent Tissue Samples and Urine

Viruses, 2021
The natural hosts of Orthohantaviruses are rodents, soricomorphs and bats, and it is well known that they may cause serious or even fatal diseases among humans worldwide.
Mónika Madai, Győző Horváth, Róbert Herczeg, Balázs Somogyi, Brigitta Zana, Fanni Földes, Gábor Kemenesi, Kornélia Kurucz, Henrietta Papp, Safia Zeghbib, Ferenc Jakab   +10 more
doaj   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

The ABCs of 4-H: A Primer for 4-H Volunteers

EDIS, 2014
This information sheet is the introduction to the 4-H Volunteer Training Series (VTS). The series contains a wealth of information, from how to start a club, to planning field trips, to how to work with youth. This 5-page fact sheet was written by Keith G. Diem, Sarah Hensley, and Ben Knowles, and published by the UF Department of 4-H Youth Development,
Keith G. Diem, Sarah Hensley, Ben Knowles   +2 more
openaire   +3 more sources

4-H Afterschool Resource Guide: Starting 4-H Clubs in After-School Programs

EDIS
This resource guide is designed to be used by Extension/4-H professionals and after-school providers to deliver well-formed, positive youth development programs in after-school sites. It includes information on initiating the development of 4-H clubs at
Sharon K. Junge, Vanessa Spero, Niki Crawson, J. R. Davis, Tara Dorn, Beth Rasa Edwards, Stacy Hall, Karen Henry, Heather Janney, Beth Kerr, Andrea Lazzari, Abby Morgan, Kristie Popa, Cindy Smalley, Melinda Souers, Katelin Stenroos, Laura Valencia, Travis West, Tracy Winters, Mary-Louise Wood   +19 more
doaj   +3 more sources

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Youth Sparks via 4-H: Relations with Program Quality, Dosage, and Involvement

Journal of Human Sciences and Extension
Using a statewide sample of participants in 4-H programs, we tested associations among youth sparks, program quality, program dosage, and four types of involvement (breadth of participation in out-of-school-time beyond 4-H, scope of learning ...
Alexandra Skrocki, Gary Ellis, Andrea Ettekal, Darlene Locke   +3 more
doaj   +1 more source

Programmatic Environmental Scans: A Survey Based on Program Planning and Evaluation Concepts

Journal of Human Sciences and Extension, 2015
Within Extension, environmental scans are most commonly used to assess community or organizational issues or for strategic planning purposes. However, Extension has expanded the use of environmental scans to systematically identify “what programs exist ...
Donna J. Peterson , Laura H. Downey, JoAnne Leatherman , Suzanne M. Le Menestrel, James Lang   +4 more
doaj   +1 more source