Results 121 to 130 of about 904,135 (284)

FGL2‐HDAC11 Drives Immunothrombosis via NETs‐Mediated Endothelial Capillarization in MASLD Fibrosis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is frequently accompanied by hepatic fibrosis and systemic cardiovascular complications; however, the mechanistic interplay between coagulation abnormalities and disease progression remains poorly defined.
Xitang Li   +16 more
wiley   +1 more source

Toward Next‐Generation High‐Speed Communication and Imaging: Solution‐Processed Sb2(S,Se)3/CdS Heterojunction for Ultrafast Self‐Powered Photodetector

open access: yesAdvanced Science, EarlyView.
A high‐quality solution‐processed Sb2(S,Se)3/CdS heterojunction is designed to overcome the intrinsic limitations of conventional photodetectors. The fabricated device achieves an excellent self‐powered performance, including a high responsivity of 0.6 A W−1, an ultrahigh specific detectivity of 7.68 × 1012 Jones, and a wide 3db bandwidth of 175 kHz ...
Xuhua Xiao   +6 more
wiley   +1 more source

Teaching volunteer educators to tinker

open access: yesCalifornia Agriculture, 2017
H. White
doaj   +1 more source

Faith-Based Institutions and High-Risk Youth [PDF]

open access: yes, 2000
Many of the highest-risk youth in poor communities are not reached by traditional youth programs, but are served by churches and other faith-based institutions that are both well-established and seriously concerned about the welfare of these vulnerable ...
Harold Dean Trulear
core  

Decoupling the Transparency‐Efficiency Trade‐Off in Semi‐Transparent Organic Solar Cells via Optimized Dual‐Channel Photoelectric Conversion

open access: yesAdvanced Science, EarlyView.
The respective roles of the heterojunction (HJ) and spontaneously formed photo‐charge (SP) channels in low‐donor‐content devices have been decoupled and subjected to a targeted optimization strategy. A breakthrough of light utilization efficiency (LUE) in semi‐transparent organic solar cells (ST‐OSCs) is achieved.
Yuyan Li   +12 more
wiley   +1 more source

Promising Practices for Working With Youth With Disabilities

open access: yesEDIS
The most recent data from the National Center for Education Statistics report that 15% of individuals aged 3–21 are served under the Individuals with Disabilities Education Act.
Vanessa Spero   +7 more
doaj   +1 more source

Supporting Success: Why and How to Improve Quality in After-School Programs [PDF]

open access: yes, 2008
This report examines the program improvement strategies, step-by-step, that allowed The James Irvine Foundation's CORAL initiative to achieve the levels of quality needed to boost the academic success of participating students.
Jessica Sheldon, Leigh Hopkins
core  

ESCRT‐Mimetic Nanodegrader Targets STING for Anti‐Inflammatory Therapy

open access: yesAdvanced Science, EarlyView.
A nanoplatform‐enabled targeted protein degradation strategy is presented to regulate aberrant STING signaling. STING‐ATTEC induces selective autophagic degradation of STING via formation of a STING–ATTEC–LC3 ternary complex, while the cationic FA‐LNP+ system enhances LC3 generation and targeted delivery. Together, this synergistic approach efficiently
Fuyuan Zhou   +9 more
wiley   +1 more source

Development of a Comprehensive New 4-H Extension Agents Training Program Using a Multi-Module Approach and the 4-H Professional Research, Knowledge, and Competencies (4HPRKC) Taxonomy [PDF]

open access: yes, 2007
Following significant budget reductions in 2002, Virginia Cooperative Extension explored strategies to meet the professional development needs of new 4-H Extension faculty and staff.
Garst, Barry A   +3 more
core   +1 more source

A Modular and Programmable Cas13d Platform for RNA Single Nucleotide Variant Detection

open access: yesAdvanced Science, EarlyView.
A scenario‐guided Cas13d platform enables configurable single nucleotide variant ribonucleic acid diagnostics through rule‐based guide design and ribonucleic acid binding domain engineering, supporting amplification‐free ultrasensitive detection and amplification‐coupled robust detection for accurate mutation classification in clinical tumor specimens.
Zeyu Wang   +8 more
wiley   +1 more source

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