Results 121 to 130 of about 98,427 (296)

Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function

Advanced Science, EarlyView.
This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang, Wenxuan Zhao, Xiaoming Hu, Yishu Wang, Peidong Yang, Diwei Zheng, Yugang Wang, Guanghui Ma, Min Shi, Wei Wei, Shuang Wang   +10 more
wiley   +1 more source

Toward Prostate Cancer Early Warning with a Self‐Powered Wearable Biosensing Platform Integrated with Machine Learning

Advanced Science, EarlyView.
ABSTRACT Current prostate cancer detection methods remain limited in non‐invasiveness and specificity, prompting interest in urinary biomarkers such as sarcosine. Here, we report a urine‐powered wearable platform for non‐invasive sarcosine detection as a proof‐of‐concept for decentralized early warning.
Jing Xu, Hanxiao Chen, Qichen Yuan, Liucun Yin, Yifang Tao, Hong Wang, Yuquan Xue, Delai Fu, Huan Pang, Tie Chong, Li Xue   +10 more
wiley   +1 more source

Teaching volunteer educators to tinker

California Agriculture, 2017
H. White
doaj   +1 more source

4-H Afterschool Resource Guide: 4-H Youth Development Programming in Hard-to-Reach Communities

EDIS
This is part of a series of guides that have been updated with permission from 4-H National Council. This resource guide is designed to be used by Extension professionals and after-school providers to deliver positive youth development programs in hard-to-reach areas or populations.
Shanon K. Junge, Abby Morgan, Kristie Popa, Cindy Smalley, Melinda Souers, Katelin Stenroos, Laura Valencia, Travis West, Tracy Winters, Andrea Lazzari, Beth Kerr, Vanessa Starr Spero, Niki Crawson, J. R. Davis, Tara Dorn, Beth Rasa Edwards, Stacy Hall, Karen Henry, Heather Janney, Mary-Louise Wood   +19 more
openaire   +1 more source

Bioorthogonal Fluorogenic Reporters for Noninvasive Imaging and Urinalysis of Immunotherapeutic Response in Renal Cell Carcinoma

Advanced Science, EarlyView.
This study reported renal‐clearable bio‐orthogonal near‐infrared fluorogenic probes (BGRs) that specifically imaging and urinalysis of granzyme B for dynamic evaluation of RCC immunotherapy. BGRs not only differentiate immunotherapeutic responses in orthotopic RCC mice, but also enable sensitive optical urinalysis of granzyme B in clinical specimens ...
Xingyue Yang, Baoshuai Liang, Liangmin Fu, Weiliang Deng, Yuyan Jiang, Weiping Xu, Jinwei Chen, Ya Zhou, Ke Wu, Jiaguo Huang   +9 more
wiley   +1 more source

Beliefs about change in the Indiana 4-H/Youth Development Program: A case study analysis

, 2000
This three-phase study utilized both qualitative and quantitative methods to document and interpret current beliefs of staff and volunteers involved in determining policy for the local 4-H Program toward the possibility of encouraging proactive change in
McKee, Renee Krieg
core  

What factors contribute to older youth retention in 4-H? [PDF]

, 2008
Includes bibliographical ...
Nutt, Bonnie L.
core  

Two‐Dimensional Triferroics: From Fundamental Couplings to Multifunctional Applications

Advanced Science, EarlyView.
This graphic summarizes the three main types of currently reported 2D triferroic couplings. From the structural perspective, existing systems can be broadly classified into two categories, which exhibit distinct symmetry features and coupling behaviors. Beyond the lattice difference, a third type involves the interplay among ferroelectricity, magnetism,
Yang Li, Jialin Gong, Zhiqing Li
wiley   +1 more source

Transferable Deep Reinforcement Learning With Edge‐Contour‐Depth Fusion for Autonomous Wireless Capsule Endoscopy Navigation

Advanced Science, EarlyView.
This study presents an anatomical landmark‐guided DRL framework for autonomous wireless capsule endoscopy navigation. Using a lightweight edge‐contour‐depth fusion module, it achieves over 97% coverage across diverse gastric anatomies. To ensure reliability, a two‐stage sim‐to‐real pipeline with an adaptive dynamic programming controller mitigates ...
Haoxuan Wu, Haitao Gao, Qingyang Liu, Sishen Yuan, Haiyang Fang, Mingwu Su, Baijia Liang, Yongzun Yang, Long Bai, Wenzhen Dong, Dihong Xie, Shijian Su, Jiewen Lai, Shing Shin Cheng, Zhen Li, Xiuli Zuo, Hongliang Ren   +16 more
wiley   +1 more source

Promising Practices for Working With Youth With Disabilities

EDIS
The most recent data from the National Center for Education Statistics report that 15% of individuals aged 3–21 are served under the Individuals with Disabilities Education Act.
Vanessa Spero, Darcy Cole, Vera Bullard, Jennifer Cushman, Tara Dorn, Kelsey Dugan, Crystal Perry, Jennifer Taylor-Winney   +7 more
doaj   +1 more source