Results 241 to 250 of about 7,227 (274)
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Synthesis of arylethylene derivatives of 2, 5-diphenyl-1, 3, 4-oxadiazole
Chemistry of Heterocyclic Compounds, 1971The synthesis of arylethylene derivatives of 2,5-diphenyl-1,3,4-oxadiazole by the Wittig reaction from 2-(p-bromomethylphenyl)-5-phenyl-1,3,4-oxadiazole and aromatic aldehydes is described. The compounds obtained fluoresce strongly on irradiation with UV light.
B. M. Krasovitskii, V. I. Grigor'eva
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Pharmacophore studies of 1, 3, 4-oxadiazole nucleus: Lead compounds as α-glucosidase inhibitors
Food and Chemical Toxicology, 2019α-glucosidase inhibition is a rational approach in the effective management of type 2 diabetes. Several inhibitors of this enzyme class are in clinical use, but are riddled with efficacy, potency and safety challenges. For this reason, new effective α-glucosidase inhibitors are under investigation.
Haroon Khan +4 more
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Anti-inflammatory and Antimicrobial Potential of 1, 3, 4-oxadiazoles and its Derivatives: A Review
Current Organic SynthesisAbstract: 1, 3, 4-oxadiazole and its derivatives have significant anti-inflammatory and antimicrobial property. Their precise mechanism of action is not known but it is postulated that they act by inhibiting the biosynthesis of certain prostaglandins.
Tarun, Chaudhary +2 more
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Poly(1, 3, 4-Oxadiazole-Amide)s Containing Pendent Phenoxy Groups
High Performance Polymers, 1996A series of new poly(1, 3, 4-oxadiazole-amide)s have been synthesized by solution polycondensation of aromatic diamines containing preformed 1, 3, 4-oxadiazole rings with phenoxyterephthalic diacid chloride or by the reaction of the same diacid chloride with p-aminobenzhydrazide resulting in a polyhydrazide-amide which was cyclodehydrated to the ...
Corneliu Hamciuc +2 more
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Synthesis Of 3-Aryl-5-[Thien-3-Yl Methyl]-1,2, 4-Oxadiazoles
Synthetic Communications, 1999Abstract A convenient and efficient synthesis of eight new compounds 5a-h is described. The intermediates 4a-h have also been isolated and characterized the with help of spectroscopic data.
R. M. Srivastava +3 more
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Asian Journal of Research in Chemistry, 2015
A Series of 2-((naphthalen-1-yl) methyl)-5-substituted-1,3,4-oxadiazole derivatives were synthesized by refluxing naphthyl acetic acid hydrazide with substituted aromatic acids in presence of phosphorous oxychloride. The intermediate naphthyl acetic acid hydrazide (2) was prepared by treatment of naphthyl acetic acid ester (1) with hydrazine hydrate ...
J Soumya, G Rajitha
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A Series of 2-((naphthalen-1-yl) methyl)-5-substituted-1,3,4-oxadiazole derivatives were synthesized by refluxing naphthyl acetic acid hydrazide with substituted aromatic acids in presence of phosphorous oxychloride. The intermediate naphthyl acetic acid hydrazide (2) was prepared by treatment of naphthyl acetic acid ester (1) with hydrazine hydrate ...
J Soumya, G Rajitha
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Design, Synthesis and Anti Cancer Evaluation of novel 1, 3, 4-oxadiazoles
Research Journal of Pharmacy and TechnologyWe designed and synthesized newer heterocyclic compounds with 1, 3, 4-thiadiazole, pyrimidine, and 1, 3, 4 -oxadiazole, with aimed to develop Histone Deacetylase (HDAC) inhibitors. The 1, 3, 4 - oxadiazole nucleus known for its diverse pharmacological properties and incorporating the thiadiazole and pyrimidine groups.
Meghna H. Seta, Monika T. Kyada
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The preparation of 1, 3, 4-oxadiazoles
Chemistry of Heterocyclic Compounds, 1970Ya. A. Levin, M. S. Skorobogatova
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Oxadiazole: A highly versatile scaffold in drug discovery
Archiv Der Pharmazie, 2022Desai Nisheeth +2 more
exaly
Microwave spectra of isotopic 1, 3, 4-oxadiazoles
Journal of Molecular Structure, 1972Lise Nygaard +5 more
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