Results 221 to 230 of about 4,363 (249)
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Study on 1, 3, 4-Oxadiazole Derivatives as an Antibacterial and Antifungal Agents
2021In the present investigation a new series of 1, 3, 4-oxadiazoles (3a-j) were synthesized by reacting INH (1) and substituted aromatic acids (2) in presence of POCl3. The new compounds were established on the basis of IR, 1H NMR and Mass spectral data.
B. C. Revanasiddappa +1 more
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A OVERVIEW ON ANTIMICROBIAL AND ANTI-INFLAMMATORY ACTIVITY OF 1, 3, 4-OXADIAZOLES
INDIAN DRUGS, 20201, 3, 4-oxadiazoles first came into the lime light about 80 years ago. With the increasing world population, the number of microbial infections has increased all over. To overcome the continuously spreading harmful microbial infections, the need for newer and newer drugs has increased tremendously.
Manpreet Kaur +4 more
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Microwave spectra of isotopic 1, 3, 4-oxadiazoles
Journal of Molecular Structure, 1972Abstract Microwave spectra of 1, 3, 4-oxadiazole and three isotopic species have been investigated. The 14 N hyperfine structure was analyzed and the nuclear quadru- pole coupling constants determined. From the centre frequencies the effective rotational constants and selected centrifugal distortion constants were computed by the least-squares ...
Lise Nygaard +5 more
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SYNTHESIS AND ANTIMICROBIAL ACTIVITIES OF SOME NEW 1, 3, 4-OXADIAZOLES
INDIAN DRUGS, 2012Various 5-β-[(N-Benzenesulphonyl/tosyl)-4-(un) substituted anilino] ethyl-2-H/CH3/C6H5/-CH2C6H5/p-NO2C6H4-1,3,4-oxadiazoles (5a-d), 5--β-[(N-Benzenesulphonyl/tosyl)-4-(un)-substituted anilino] ethyl-2-(N,N-diethylamino/anilino/morpholino)-1, 3, 4-oxadiazoles (6a-r), 3--β-[(N-Benzenesulphonyl/tosyl)-4-(un) substituted anilino] ethyl-4-amino-5-mercapto-4(
S. R. Desai, U. V. Laddi
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Synthesis of arylethylene derivatives of 2, 5-diphenyl-1, 3, 4-oxadiazole [PDF]
Chemistry of Heterocyclic Compounds, 1971 The synthesis of arylethylene derivatives of 2,5-diphenyl-1,3,4-oxadiazole by the Wittig reaction from 2-(p-bromomethylphenyl)-5-phenyl-1,3,4-oxadiazole and aromatic aldehydes is described. The compounds obtained fluoresce strongly on irradiation with UV light.
V. I. Grigor'eva, B. M. Krasovitskii
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Recent Advances in 1, 3, 4-Oxadiazole Chemistry
1967Publisher Summary This chapter introduces the chemistry of the 1,3,4-oxadiazoles. The 1,3,4-oxadiazoles have large number of applications in diverse areas—for example, in drug syntheses, scintillation materials, and the dyestuffs industry. Ring cleavage reactions of the 1,3,4-oxadiazoles have also excited great interest in various fields, because ...
K. Möckel, A. Hetzheim
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Poly(1, 3, 4-Oxadiazole-Amide)s Containing Pendent Phenoxy Groups
High Performance Polymers, 1996A series of new poly(1, 3, 4-oxadiazole-amide)s have been synthesized by solution polycondensation of aromatic diamines containing preformed 1, 3, 4-oxadiazole rings with phenoxyterephthalic diacid chloride or by the reaction of the same diacid chloride with p-aminobenzhydrazide resulting in a polyhydrazide-amide which was cyclodehydrated to the ...
Corneliu Hamciuc +2 more
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Synthesis and biological evaluation of 1, 2, 4‐oxadiazole derivatives as novel GPR119 agonists
Chemical Biology & Drug Design, 2016A series of 1, 2, 4‐oxadiazole derivatives have been designed and synthesized, and 25 compounds were evaluated their abilities by the assay of cAMP concentration in GPR119‐transfected HEK293T cells. All compounds showed acceptable agonistic effects on GPR119. Among these compounds, 4p exhibited the best agonistic effects with the EC50 of 20.6 nm, which
Liang Ma +4 more
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Synthesis of Some New 1, 3, 4-Oxadiazole, Pyrazole, and Pyrimidine Bearing Thienopyrazole Moieties
Current Organic Synthesis, 2020Aim and Objective: According to the literature survey, pyrazole is a unique template that is associated with several biological activities. This article highlighted the research work of many researchers reported in the literature for synthesis and different pharmacological activities of the pyrazole nucleus.
Mohamed Ahmed Elian Sophy +1 more
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1976
Publisher Summary This chapter focuses on the chemistry of 1,2,4-oxadiazoles and the corresponding reduced derivatives. The chapter discusses the synthesis of 1,2,4-oxadiazoles. Two widely used general methods of synthesizing 1,2,4-oxadiazoles embrace 95% of the practical preparations of these compounds: The conversion of amidoximes by means of ...
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Publisher Summary This chapter focuses on the chemistry of 1,2,4-oxadiazoles and the corresponding reduced derivatives. The chapter discusses the synthesis of 1,2,4-oxadiazoles. Two widely used general methods of synthesizing 1,2,4-oxadiazoles embrace 95% of the practical preparations of these compounds: The conversion of amidoximes by means of ...
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