Results 251 to 260 of about 11,453,687 (274)
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Journal of Organic Chemistry, 2013
A highly efficient one-pot synthesis of enantiomerically enriched 2-aryl-2,3-dihydroquinolin-4(1H)-ones has been carried out for the first time using per-6-ABCD as a supramolecular host, chiral base catalyst, and a reusable promoter to give the ...
Kuppusamy Kanagaraj, K. Pitchumani
semanticscholar +1 more source
A highly efficient one-pot synthesis of enantiomerically enriched 2-aryl-2,3-dihydroquinolin-4(1H)-ones has been carried out for the first time using per-6-ABCD as a supramolecular host, chiral base catalyst, and a reusable promoter to give the ...
Kuppusamy Kanagaraj, K. Pitchumani
semanticscholar +1 more source
ChemInform Abstract: Synthesis of 4‐Quinolone Derivatives.
ChemInform, 1995AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
K. B. G. Torssell, S. Jensen
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Synthesis of 6-aryl substituted 4-quinolones via Suzuki cross coupling
, 2014A convenient way to introduce aryl functionalization in the 6-position of 4-quinolones is developed via selective bromination and subsequent arylation by Suzuki cross-coupling. Ethyl 4-quinolone 3-carboxylates were subjected to selective bromination at C-
S. Gupta, P. Ghosh, S. Dwivedi, S. Das
semanticscholar +1 more source
Mechanisms of resistance to the 4-quinolone antibacterial agents
Journal of Antimicrobial Chemotherapy, 1990Because of the close structural relationship of the fluorinated 4-quinolones to the parent compound nalidixic acid the mechanism of resistance is often perceived to be the same. However, it is clear that whilst the mechanism of resistance to fluorinated 4-quinolones is essentially the same, strains that are selected as resistant to nalidixic acid ...
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Detection of 2-Alkyl-4-Quinolones Using Biosensors
20102-alkyl-4-quinolones (AQs) such as 2-heptyl-3-hydroxy-4-quinolone (PQS) and 2-heptyl-4-quinolone (HHQ) are quorum sensing signal molecules. Here we describe two methods for AQ detection and quantification that employ thin layer chromatography (TLC) and microtitre plate assays in combination with a lux-based Pseudomonas aeruginosa AQ biosensor strain ...
Miguel Cámara+3 more
openaire +4 more sources
, 2012
The Buchwald–Hartwig coupling/Michael addition sequence has been successfully applied to the synthesis of functionalized 1,2-disubstituted 4-quinolones using Pd(OAc)2 as a catalyst and PPh3 as a ligand.
Xiang-Dong Fei+4 more
semanticscholar +1 more source
The Buchwald–Hartwig coupling/Michael addition sequence has been successfully applied to the synthesis of functionalized 1,2-disubstituted 4-quinolones using Pd(OAc)2 as a catalyst and PPh3 as a ligand.
Xiang-Dong Fei+4 more
semanticscholar +1 more source
Cycloaddition reactions of N-alkoxycarbonyl-4-quinolones
Tetrahedron, 1989AbstractIn connection with the search for anthracycline analogues which retain the cytotoxicity but possess negligible cardiotoxicity, structures modified in ring C to give non‐reducible analogues of anthracyclines are required.
John R Nicholson+3 more
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Synthesis of N-Alkyl-Substituted 4-Quinolones via Tandem Alkenyl and Aryl C–N Bond Formation
, 2012N-Alkyl-substituted 4-quinolones are present as the key structural motif in many marketed drugs. An efficient one-step tandem amination approach was developed to afford N-alkyl-substituted 4-quinolones in high yields from easily accessible o-chloroaryl ...
J. Shao+4 more
semanticscholar +1 more source
K2CO3-catalyzed synthesis of chromones and 4-quinolones through the cleavage of aromatic C-O bonds.
Organic Letters, 2012Phenol-derived electrophiles are favorable substrates because phenols are naturally abundant or can be readily prepared from other aromatic compounds. However, the cleavage of aromatic C-O bonds is a great challenge because of their high energy. K(2)CO(3)
Jie Zhao, Yufen Zhao, H. Fu
semanticscholar +1 more source
ChemInform Abstract: An Efficient Synthesis of Di‐ and Trimethoxy‐4‐quinolones.
ChemInform, 1994AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
R. Negishi+6 more
openaire +3 more sources