Results 121 to 130 of about 18,072,997 (323)
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova+26 more
wiley +1 more source
P3‐081: Education halves the risk of dementia due to apolipoprotein ∊4 allele: A collaborative study from the Swedish brain power initiative [PDF]
Hui‐Xin Wang+6 more
openalex +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero+8 more
wiley +1 more source
4. Survey of Early Retirement Practices in Higher Education
John E. Keefe
openalex +2 more sources
Private and public economic returns for a male obtaining an upper secondary or post-secondary non-tertiary education, ISCED 3/4, and obtaining a tertiary education, ISCED 5/6, as part of initial education (2006) [PDF]
openalex +1 more source
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh+5 more
wiley +1 more source
Multicultural Education In Elementary Music Education Textbooks (Grades 1-4)
In this study, the elementary music education textbooks which are published for use in the first stage of elementary education (1st-4th grades) in Turkey were examined in terms of multicultural elements they contain. Student workbooks for each grade were evaluated and analysed using the document review method according to the categories established by ...
openaire +2 more sources
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha+10 more
wiley +1 more source