Results 191 to 200 of about 10,060,116 (342)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
4 Effective communication and leadership in nutrition research & education
Celia Laur +4 more
doaj +1 more source
Assessment of an Interactive Online Asynchronous Pediatric-Focused Toxicology Curriculum. [PDF]
Appenteng R +3 more
europepmc +1 more source
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Developing a Best Practice Guideline for Clinical Practice in a Digital Health Environment: Systematic Reviews Based on the Grading of Recommendations, Assessment, Development, and Evaluation Approach. [PDF]
Bailey L +6 more
europepmc +1 more source
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
The Education Act 2011 (commencement no. 4 and transitional and savings provisions) order 2012 [PDF]
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