Results 261 to 270 of about 9,727,270 (342)

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Education debt and household consumption upgrading: Positive incentives or inhibitions? [PDF]

PLoS One
Xie M, Chen X, Zhao Y.
europepmc   +1 more source

Data availability for the calculation of SDG 4-Education 2030 indicators : Analysis covering Latin America and the Caribbean. Information paper no. 30

, 2016

openalex   +1 more source

The Nebraska Educator Volume 4: 2017

The Nebraska Educator, 2018
Abraham E. Flanigan, Zoe Falls
openaire   +2 more sources

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Nutritional education interventions on the components of metabolic syndrome in the North-Western Bangladeshi adults. [PDF]

BMC Nutr
Akter S, Azhar BS, Kamruzzaman M, Al Banna MH, Hasan H, Roshid MM.   +5 more
europepmc   +1 more source

Helping the Next 4 Billion Go Online Part II: Prototyping Solutions for Digital Literacy Education

, 2017
Victor Udoewa, Neil Mathew, Anuranjan Gupta, Lea Bauer, Lokesh Bhog, Bhawana Prabhakar, Parivartika Patel, Louie Al-Hafidh   +7 more
openalex   +2 more sources

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

ChatGPT in Medical Education: Bibliometric and Visual Analysis.

JMIR Med Educ
Zhang Y, Xie X, Xu Q.
europepmc   +1 more source

Knowing Me Knowing You-Mentorship in Hospital Placement. [PDF]

Clin Teach
Kvernenes M, Grimstad H, Schei E, Thyness C, Dornan T, Stenfors T.   +5 more
europepmc   +1 more source