Results 51 to 60 of about 7,780,605 (213)
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Standards and Testing Agency annual report and financial statements 2012-2013: (for the year ended 31 March 2013) [PDF]
Enabling power: Education Act 1996, s. 537A (4) (5) (6). Issued: 29.05.2013. Made: 20.05.2013. Laid: 29.05.2013. Coming into force: 28.06.2013. Effect: S.I. 2009/1563 amended.
Todd, Ian
core
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
The Education (Individual Pupil Information) (Prescribed Persons) (England) (Amendment) Regulations 2013 [PDF]
Enabling power: Education Act 1996, s. 537A (4) (5) (6). Issued: 29.05.2013. Made: 20.05.2013. Laid: 29.05.2013. Coming into force: 28.06.2013. Effect: S.I. 2009/1563 amended.
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Girls' career aspirations [PDF]
"This report evaluates the extent to which careers education, guidance and other provision raise aspirations and inform the choices of courses and careers by girls and young women to support their long-term achievement.
core
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Does Preoperative Ostomy Education Decrease Anxiety in the New Ostomy Patient? [PDF]
Background: There are approximately 100,000 patients with new ileostomies and colostomies created in the United States each year. These patients have specialized needs that include acceptance of altered body image, psychological stress, learning of ...
Harris, Michelle Suzann
core +1 more source
Understanding How Students Use Physical Ideas in Introductory Biology Courses
The University of Maryland (UMD) Biology Education and Physics Education Research Groups are investigating students' views on the role of physics in introductory biology courses.
Cooke, Todd +3 more
core +1 more source

