4. Liberal Education and the Capitalocene in American Higher Education
Data-driven control is remaking American higher education as the Capitalocene is remaking environment around us. In higher education, how might we orientate the queer potential of liberal education to produce the conditions of possibility of an Earth beyond the Capitalocene and data-driven control, an Earth that produces expansive notions of student ...
openaire +3 more sources
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
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Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma+9 more
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A Defence of Classical Education. By R. W. Livingstone. 278 pp. Macmillan & Co., 1916. 4s. 6d. net. [PDF]
R. W. Livingstone
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This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh+8 more
wiley +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
wiley +1 more source
The Politics of Soviet Policy Formation: Khrushchev's Innovative Policies in Education and Agriculture. By James B. Bruce. Monograph Series in World Affairs, vol. 13: Change and Survival: Studies in Social Dynamics in Eastern Europe and the Soviet Union. Essays in Honor of Josef Korbel, Book 4. Denver: University of Denver, Graduate School of International Studies, 1976. xx, 138 pp. Paper. [PDF]
George W. Breslauer
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The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
wiley +1 more source
Puzzle maths, by R. D. Hollands, R. J. Elder and R. A. Edwards. Books 1,2. £4·50 each. 1977. SBN 0 333 19973 1/19975 8 (Macmillan Education) [PDF]
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Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte+10 more
wiley +1 more source