Results 131 to 140 of about 8,659,232 (388)

Influence of physicochemical properties and structure of mixed solvents propylene glycol – macrogol 400 on their in vitro release

, 2023
Elena Bezuglaya, Alla Krasnopyorova, Anna Liapunova, Igor Zinchenko, Nikolay Lyapunov, Oksana Sytnik   +5 more
openalex   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Effects of synchronous music on 400-metre sprint performance [PDF]

, 2006
The aim of the present study was to assess the effects of motivating and oudeterous (neither motivating nor demotivating) synchronous music on 400-m sprint performance while controlling for the potential confound of pre-performance mood.
Karageorghis, CI, Simpson, SD
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Certainty of Punishment versus Severity of Punishment- An Experimental Investigation [PDF]

Compliance with laws and regulations depends on the expected penalty facing violators. The expected penalty depends on both the probability of punishment and the severity of the punishment if caught. A key question in the economics of crime literature is
Lana Friesen
core  

Superficial processing of explicit inferences in text [PDF]

, 1977
Research reported herein was supported in part by the National Institute of Education. US-NIE-C-400-76-0116Includes bibliographical references (leaf 20)Research reported herein was supported in part by the National Institute of Education. US-NIE-C-400-76-
Esposito, Joseph J., Spiro, Rand J.
core  

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Dark Matter Search Perspectives with GAMMA-400

, 2013
GAMMA-400 is a future high-energy gamma-ray telescope, designed to measure the fluxes of gamma-rays and cosmic-ray electrons + positrons, which can be produced by annihilation or decay of dark matter particles, and to survey the celestial sphere in order
Adriani, O., Aptekar, R. L., Arkhangelskaja, I. V., Arkhangelskiy, A. I., Avanesov, G. A., Bergstrom, L., Boezio, M., Bonvicini, V., Boyarchuk, K. A., Dogiel, V. A., Fradkin, M. I., Fuglesang, Ch., Galper, A. M., Gusakov, Yu. V., Hnatyk, B. I., Kachanov, V. A., Kaplin, V. A., Kheymits, M. D., Korepanov, V., Larsson, J., Leonov, A. A., Longo, F., Maestro, P., Marrocchesi, P., Mazets, E. P., Mikhailov, V. V., Mocchiutti, E., Moiseev, A. A., Mori, N., Moskalenko, I., Naumov, P. Yu., Papini, P., Pearce, M., Picozza, P., Runtso, M. F., Ryde, F., Sparvoli, R., Spillantini, P., Suchkov, S. I., Tavani, M., Topchiev, N. P., Vacchi, A., Vannuccini, E., Yurkin, Yu. T., Zampa, N., Zarikashvili, V. N., Zverev, V. G.   +46 more
core  

The 400-Hz aircraft power-generation systems: Advancing the baseline [PDF]

, 1983
Today's benchmark system for the Boeing 757/767/A310 airplanes and future trends in hydromechanical aircraft power generating systems are discussed. The 757/767/A310 system represents the commercial state of the art and the direction in which Sundstrand ...
Glennon, T.
core   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source