Results 131 to 140 of about 8,196,263 (389)

IMMUNOSUPPRESSION IN BROILERS EXPOSED TO INCREASED TEMPERATURE [PDF]

open access: yesJournal of Veterinary and Animal Sciences, 1998
Effect of prolonged and intermittent exposure to increased atmospheric temperature on the immune responses was studiedexperimentally in 154 broilers. It was observed that 40 ± 1 ° C for 29 days, 12 h.
S.J. Jamadar   +4 more
doaj  

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald   +18 more
wiley   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

El desajuste financiero y la elección de régimen cambiario [PDF]

open access: yes
(Disponible en idioma inglés únicamente) El desajuste financiero se está convirtiendo en algo corriente en América Latina. Los años 90 se caracterizaron por una gran inestabilidad en la magnitud y el costo de los flujos de capitales.
Carmen Pagés-Serra   +3 more
core  

Sequential Therapy in Metastatic Renal Cell Carcinoma

open access: yesJournal of Kidney Cancer and VHL, 2016
The treatment of metastatic renal cell carcinoma (mRCC) has changed dramatically in the past decade. As the number of available agents, and related volume of research, has grown, it is increasingly complex to know how to optimally treat patients.
Bradford R Hirsch   +7 more
doaj   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

Understanding Solar Activity During the Last 400 Years [PDF]

open access: yes, 2019
The solar cycle has a profound effect on both terrestrial and extra-terrestrial operations. Understanding the history of the solar cycle is necessary for studying long term trends, however older data is difficult to calibrate due to the sparsity of ...
Hollenbach, Sam Q
core   +1 more source

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