Results 101 to 110 of about 244,532 (174)

Inhalable Polymeric Nanoparticle Containing Triphenylphosphanium Bromide‐modified Sonosensitizer for Enhanced Therapy of Acute Bacterial Pneumonia

Advanced Science, EarlyView.
Bacterial pneumonia is the sixth leading cause of death. In this study, an inhalable polymeric nanoparticle NPFCPS‐P is developed, which under US stimulation showed high efficacy in the treatment of acute bacterial pneumonia. This nanoplatform would be much less prone to select bacterial resistance and represented a promising measure for antibiotics ...
Lin Wang, Fangzhou Chen, Nier Wu, Lingfei Hu, Haihua Xiao, Hanchen Zhang, Dongsheng Zhou   +6 more
wiley   +1 more source

A Real‐Time Cell Death Self‐Reporting Theranostic Agent for Dynamic Optimization of Photodynamic Therapy

Advanced Science, EarlyView.
A cell death self‐reporting photodynamic theranostic nanoagent (CDPN) is developed that integrates photodynamic therapy (PDT) with real‐time K⁺ imaging to provide timely feedback on treatment responses. This approach enables the optimization of the drug‐light interval (DLI), a critical factor in PDT, resulting in significantly enhanced antitumor ...
Wei Bian, Qiyue Wang, Cui He, Pan Tao, Juanjuan Zheng, Yulu Zhang, Jing Li, Fangyuan Li, Hongyan Jia, Daishun Ling   +9 more
wiley   +1 more source

CaMKK2 Regulates Macrophage Polarization Induced by Matrix Stiffness: Implications for Shaping the Immune Response in Stiffened Tissues

Advanced Science, EarlyView.
Macrophage phenotypes are influenced by the microenvironment. Matrix stiffness, a key ECM factor, polarizes macrophage toward a pro‐regenerative phenotype in a 3D physiological environment. CaMKK2 selectively regulates stiffness‐induced macrophage polarization, impacting tumor growth and wound healing.
Ya Guan, Min Zhang, Jiyeon Song, Marcos Negrete, Tyler Adcock, Reeva Kandel, Luigi Racioppi, Sharon Gerecht   +7 more
wiley   +1 more source

Mesothelioma risks and cumulative exposure to elongate mineral particles of various sizes in Minnesota taconite mining industry. [PDF]

Occup Environ Med
Shao Y, Ramachandran G, Mandel JH, MacLehose RF, Alexander BH.   +4 more
europepmc   +1 more source

Solution‐Processable Van Der Waals Heterojunctions on Silicon for Self‐Powered Photodetectors with High Responsivity and Detectivity

Advanced Science, EarlyView.
This work reports an all‐solution processable fabrication approach for fabricating Ti3C2Tx/Cu3(HHTP)2/n‐Si heterojunction as self‐powered photodetectors through the consecutive spray coating a Cu3(HHTP)2 and Ti3C2Tx thin films on n‐type silicon surface, as formed self‐supplied photodetector reveals exceptional responsivity and detectivity.
Yuansheng Ge, Da Lei, Chaojun Zhang, Quan Zhang, Jinlong Mu, Jing Li   +5 more
wiley   +1 more source

Investigating the structural properties and wear resistance of martensitic stainless steels. [PDF]

PLoS One
Bhadauria A, Reddy KV, Khatirkar RK, Bandhu D, Gangwar PK.   +4 more
europepmc   +1 more source

Identification of CD38high Monocyte as a Candidate Diagnostic Biomarker and Therapeutic Target for Sepsis

Advanced Science, EarlyView.
This study uncovers that CD38high monocytes discriminate sepsis and sterile inflammation and are associated with 28‐day mortality in bacterial sepsis. Targeting CD38 therapy reduces inflammatory response in monocytes and in sepsis mice model. Mechanistically, CD38‐HIF‐1α/glycolysis/MGO loop exacerbates sepsis‐induced immune dysregulation.
Ning Hua, Limin Kong, Li Fan, Yanan Bai, Yujun Zhou, Yanfang Zhang, Qingwei Zhao, Xiaoyang Lu, Hongyu Yang, Hangyang Li, Peili Ding, Yuyu Nan, Qinghua Ji, Ping Yang, Lu Li, Yijing Xin, Lijuan Zhao, Wei Yang, Wenqiao Yu, Saiping Jiang   +19 more
wiley   +1 more source

Prevalence of katG and inhA mutations associated with isoniazid resistance in Mycobacterium tuberculosis clinical isolates in Cameroon. [PDF]

BMC Microbiol
Nono VN, Nantia EA, Mutshembele A, Teagho SN, Simo YWK, Takong BS, Djieugoue YJ, Assolo YP, Ongboulal SM, Awungafac SN, Eyangoh S, Mensah E, Makhado NA, Donfack VFD.   +13 more
europepmc   +1 more source

The Function of Photocatalytic Performance and Carrier Separation Efficiency Tuned by Doping Content in Homogeneous Photocatalysts

Advanced Science, EarlyView.
A doping model of homogeneous photocatalysts of TiO2 is constructed to directly show the mapping relationship between carrier separation efficiency and photocatalytic performance. TRPL, KPFM, fs‐TAS measurements further quantify the carrier dynamics process. The photocatalytic performance of this series samples is dominated by the optimal conditions of
Chunxia Wen, Xinyue Ni, Mei Han, Yue Yu, Chuanqiang Liu, Yuan Zhang, Beining Zheng, Shouhua Feng   +7 more
wiley   +1 more source

Unveiling the multifaceted nature of terpyridine-based metal complexes: a synergistic study of their photophysical and electrochemical behavior with computational insights. [PDF]

RSC Adv
Naeem N, Mughal EU, Bozkurt E, Ahmed I, Zafar MN, Ayub AR, Sadiq A, Alsimaree AA, Alsantali RI, Ahmed SA.   +9 more
europepmc   +1 more source