Results 271 to 280 of about 2,478,339 (383)

Incidence and Management of Adverse Events Associated with Tebentafusp Treatment in Metastatic Uveal Melanoma: Pooled Safety Analysis of 410 Patients. [PDF]

open access: yesClin Cancer Res
Sato T   +20 more
europepmc   +1 more source

Biomimetic Iridium‐Based Photothermal Nanozyme to Trigger Ferroptosis and Pyroptosis and Activate the cGAS‐STING Pathway for Improved Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study develops an iridium‐based nanozyme (IIN@M) with superior enzyme‐like activity and photothermal performance. It disrupts intracellular redox balance by generating reactive oxygen species and depleting glutathione, which synergistically induces ferroptosis, pyroptosis, and immunogenic cell death.
Lijun Ding   +7 more
wiley   +1 more source

Ultrafine Ru‐M Alloy@S Vacancy‐Rich MoS2 Nanosheets With Bimetallic Active Sites for Efficient Hydrogen Evolution in Alkaline and Acidic Media

open access: yesAdvanced Science, EarlyView.
A USMR synthesizes ultrafine RuCo alloy on S‐vacancy‐rich 1T phase MoS2. This method enables rapid precursor mixing, instantaneous reduction, and uniform alloy dispersion while creating S vacancies. The synergy between Ru‐Co sites and defective MoS2 optimizes hydrogen kinetics, achieving a low overpotential of 31 mV@10 mA·cm‐2 in acid, providing a ...
Rui Su   +11 more
wiley   +1 more source

Precision‐Engineered Silver Single‐Atom Carbon Dot Nanozymes for Theranostic Management of Acute Kidney Injury

open access: yesAdvanced Science, EarlyView.
Mitochondria‐targeted silver single‐atom carbon dot (T‐AgSA‐CDs) nanozymes enable dual SOD/GPx‐like ROS scavenging, real‐time imaging, and therapeutic effects for acute kidney injury (AKI). Atomically dispersed Ag sites synergize with carbon dots to restore renal redox hemostasis, protect mitochondrial function, mitigate inflammation, facilitate post ...
Tianle Tang   +10 more
wiley   +1 more source

Correction: CUGBP Elav-like family member 4 promotes cardiac remodeling through inhibition of FMO2. [PDF]

open access: yesBMC Cardiovasc Disord
Zhang X   +6 more
europepmc   +1 more source

Reprogramming M2b Macrophages via GPX1 Activation by Selenium Nanoparticles Attenuates Lupus Nephritis

open access: yesAdvanced Science, EarlyView.
SeZM NPs selectively target M2b macrophages through mannose–MRC1 (CD206) recognition, enhance GPX1 biosynthesis, and suppress mitochondrial ROS generation, oxidative stress, and JAK–STAT signaling. This dual regulation reduces pro‐inflammatory cytokine release, limits immune cell infiltration and fibrosis, and preserves renal function, providing a ...
Haoran Lv   +16 more
wiley   +1 more source

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