Results 121 to 130 of about 324,595 (247)

AI‐Designed Cyclic Peptides Enable Controllable Modulation of the CD28 Immune Checkpoint

Advanced Science, EarlyView.
AI‐designed cyclic peptides enable controllable modulation of the CD28 immune checkpoint through reversible disruption of CD28‐CD80/CD86 interactions. The lead peptide, CIP‐3, suppresses T‐cell activation without intrinsic agonist activity, demonstrates dose‐dependent efficacy in a murine colitis model, and attenuates inflammatory cytokine production ...
Katarzyna Kuncewicz, Saurabh Upadhyay, Renjie Zhu, Hongliang Duan, Moustafa T. Gabr   +4 more
wiley   +1 more source

Photocaged Chloroquine Derivatives for the Light-Dependent Inhibition of Autophagy in Cancer Stem Cells. [PDF]

ACS Chem Biol
Alonso-Manresa S, Serra C, Muñoz L, Bataller M, Garcia-Mayea Y, Lleonart Pajarin ME, Garcia Prats B, Mancilla Zamora S, Diaz Riascos ZV, Llebaria A, Josa-Culleré L.   +10 more
europepmc   +1 more source

Automated Extraction of Multicomponent Alloy Data Using Large Language Models for Sustainable Design

Advanced Science, EarlyView.
A large language model (LLM) based pipeline is developed to automatically extract a comprehensive and accurate multicomponent alloy database from literature corpus. The extracted dataset is integrated with sustainability indicators to identify potential alloys that outperform existing industrial benchmark materials in terms of both performance and ...
Aravindan Kamatchi Sundaram, Mohit Chakraborty, Sai Mani Kumar Devathi, B. Pabitramohan Prusty, Rohit Batra   +4 more
wiley   +1 more source

Unusual Thermally Induced Blueshift and Emission Amplification of Mn2+ Ions Enable Filter‐Free Luminescent Thermal Imaging

Advanced Science, EarlyView.
ABSTRACT The shift from point‐based thermal sensing to filter‐free thermal imaging requires luminescent thermometers that exhibit pronounced and thermally driven spectral changes within spectral regions matching the sensitivity profiles of the red, green and blue (RGB) channels of a digital camera.
Y. Abe, M. Szymczak, J. Zeler, L. Marciniak   +3 more
wiley   +1 more source

On-Body and Off-Body Communications: A Comparative Study Between Hardware and Simulations. [PDF]

Sensors (Basel)
Oza D, Ramonet AG, Yoshida M, Noguchi T.
europepmc   +1 more source

Dynamic Evolution‐Controlled Parabolic‐Shaped Microstructures for Ultra‐Black Surface via Self‐Assembled Microsphere Mask Etching

Advanced Science, EarlyView.
A robust, substrate‐independent fabrication approach overcomes the spectral and geometric limitations of traditional stray‐light suppression. By combining ink spray‐coating with self‐assembled microsphere mask etching, this method produces parabolic‐shaped microstructures on diverse planar and curved engineering components.
Yiming Li, Jianwei Wang, Guoxu Yu, Qunbo Lv, Yuan Ma, Jiadao Wang   +5 more
wiley   +1 more source

PRSS23 promotes ovarian cancer peritoneal dissemination independent of protease activity. [PDF]

J Biol Chem
Akhtar S, Coban M, Miller E, Hockla A, Maina E, Mehner C, Ilic S, Papo N, Radisky DC, Radisky ES.   +9 more
europepmc   +1 more source

A Ceramic Network for Hybrid Solid Electrolyte Lithium Metal Batteries

Advanced Science, EarlyView.
An in‐plane aligned Ta‐LLZO ceramic network exhibits superior performance compared to conventional fillers, including single ceramic fibers and particles. The tortuosity within the polymeric phase of hybrid solid electrolytes is identified as a key parameter governing lithium‐ion transport pathways and dendrite suppression.
Luca Weckelmann, Jeong Seop Yoon, Jehad Ahmed, Krzysztof Dzieciol, Anna Windmüller, Luc Raijmakers, Sanja Tepavcevic, Hans Kungl, Venkat Srinivasan, Chih‐Long Tsai, Rüdiger‐A. Eichel   +10 more
wiley   +1 more source

Advanced functional porous materials for photocatalytic H₂O₂ production. [PDF]

Chem Sci
Rasaily S, K Dam G, Ghosh SK.
europepmc   +1 more source

Placental Site Trophoblastic Tumor Acquires Immune Functions by Incorporating Host Maternal Genes

Advanced Science, EarlyView.
PSTT cells, through cell fusion with B cells, incorporate abundant non‐inherited maternal genes that are detectable by DNIMA. These hybrid cells acquire immunotherapy‐resistant genetic changes and increase the expression of B cell‐derived immune‐related molecules such as Ig, HLA, LILRB, SIGLEC10, and so on, creating an immunotolerant environment around
Kyosuke Kagami, Masanori Ono, Yasunari Mizumoto, Tatsuhito Kanda, Takashi Iizuka, Takiko Daikoku, Shin‐ichi Horike, Akira Hattori, Akihito Horie, Sachiko Minamiguchi, Tomoko Fujiwara, Kazuyoshi Hosomichi, Atsushi Tajima, Hirokazu Usui, Kaoru Abiko, Hiroshi Fujiwara   +15 more
wiley   +1 more source