Results 51 to 60 of about 1,410,394 (298)

Revisiting Nurse Rivers

open access: yesVoices in Bioethics, 2013
The Tuskegee syphilis study’s most enduring figure is also one of its most intriguing. Nurse Eunice Rivers was instrumental to the study for both procuring its members and then keeping them involved in it.
Lisa Kearns
doaj   +1 more source

ПОСТСТРЕССОВЫЕ РЕАКЦИИ И РАССТРОЙСТВА У УЧАСТНИКОВ ВОЙНЫ В АРЦАХЕ / POST-STRESS REACTIONS AND DISORDERS AMONG THE PARTICIPANTS OF THE WAR IN ARTSAKH

open access: yesARMENIAN JOURNAL OF MENTAL HEALTH, 2023
Relevance: Psychological trauma and stress-related disorders represent the primary challenges in modern psychiatry, notably acute stress disorder (ASD) and post-traumatic stress disorder (PTSD).
S. G. Sukiasyan   +3 more
semanticscholar   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

The Immediate Mental Health Effects of the 2020 Artsakh War on Armenians: A Cross-Sectional Study

open access: yesInternational Journal of Psychiatry Research, 2022
Background: While previous studies show the long-term and transgenerational effects of war on mental health, immediate effects on mental health are relatively understudied.
Ani S. Movsisyan   +4 more
semanticscholar   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Prospects for Digitalization of Higer Education in Armenia in the Context of Post-pandemic and Post-war Transformations

open access: yesStudia Warmińskie
This article examines the challenges and opportunities of digitalizing higher education in Armenia in the context of the COVID-19 pandemic and the aftermath of the 44-day war in 2020 (Nagorno Karabahh Conflict).
Marek Sokołowski   +2 more
doaj   +1 more source

The Cowl - v.7 - n.12 - Jan 16, 1942 [PDF]

open access: yes, 1942
The Cowl - student newspaper of Providence College. Volume 7, Number 12 - Jan 16, 1942.

core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

The Strategic Genius: Securing Victory Outside the Battlefield

open access: yesSocial Development & Security
Purpose. To examine the “winning without fighting” strategy, its contemporary relevance, and its application in the Second Karabakh War. Method.  comparative analysis, and synthesis. Findings.
Rashad Tahirov, Khayal Iskandarov
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

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