Results 61 to 70 of about 1,297,917 (256)

Shooting the War: The Canadian Army Film Unit in the Second World War [PDF]

open access: yes, 2012
Very little has been written about the Canadian Army Film Unit (CAFU) since the end of the Second World War, despite Jon Farrell’s postulation. There have been a few short newspaper articles related to teh Film Unit and the D-Day footage that made it ...
Klotz, Sarah
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Home Front to War Front: The Navy Nurse Corps During World War II [PDF]

open access: yes, 2016
The Navy Nurse Corps was created in 1908, when President Theodore Roosevelt signed the Naval Appropriations Bill. Twenty women were selected to become the corps’ first members. These women were referred to as the “The Sacred Twenty.” On December 7, 1941,
Thibault, Amanda L.
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The Memory of Battle Surrounds You Once Again: Iowa Grand Army of the Republic Reunions and the Formation of a Pro-Union Nationalism, 1886-1949

open access: yes, 2015
Following the bloody years of the Civil War, veteran organizations became a breeding ground for nationalism making and memory shaping. Historians, like Caroline Janney and David Blight, have debated what these memories meant for northern veterans.
Bautz, Peter
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

The Punishment for Apostasy in an Established Islamic Tradition

open access: yesThe Islamic Culture, 2018
The punishment for apostasy is an established Islamic Tradition THe writes,All Muslim j urists agree that the apostate is to be puni.shed. How ever, they differ regarding the punishment itself.
Hafiz Shabbir Ahmed Jamie   +1 more
doaj  

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