Results 61 to 70 of about 3,198 (197)

Reinforcement Learning for Jump‐Diffusions, With Financial Applications

Mathematical Finance, EarlyView.
ABSTRACT We study continuous‐time reinforcement learning (RL) for stochastic control in which system dynamics are governed by jump‐diffusion processes. We formulate an entropy‐regularized exploratory control problem with stochastic policies to capture the exploration–exploitation balance essential for RL.
Xuefeng Gao, Lingfei Li, Xun Yu Zhou
wiley   +1 more source

Analisis Mutasi Gen SRY dan AZF serta Fungsi Gonad pada Penderita 46,XY Disorder of Sex Development (DSD)

, 2017
Disorder of sex development (DSD) includes congenital conditions in which development of chromosomal,gonadal or anatomy of urogenital is atypical. SRY and AZF genes have relationships with sex development andfertility in 46,XY DSD patients.
Sultana MH Faradz, Ahmad Zulfa Juniarto, Tri Indah Winarni, Meira Erawati, Ardy Santosa   +4 more
core   +1 more source

Clinical and molecular spectrum of 46,XY disorders of sex development that harbour MAMLD1 variations: case series and review of literature

Orphanet Journal of Rare Diseases, 2020
Background Mastermind-like domain-containing 1 (MAMLD1) has previously been identified as a causative gene for “46,XY Disorders of Sex Development (DSD)”. Recently, there has been some controversy regarding the causative role of MAMLD1 variations in DSDs.
Lele Li, Chang Su, Lijun Fan, Fenqi Gao, Xuejun Liang, Chunxiu Gong   +5 more
doaj   +1 more source

Genetic Characterization and Multidisciplinary Management of Complete Androgen Insensitivity Syndrome: Unveiling a Novel AR Mutation

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT A novel AR frameshift mutation (c.2023_2035del) was identified in a 17‐year‐old phenotypic female with Complete Androgen Insensitivity Syndrome (CAIS). This report emphasizes the necessity of molecular characterization and multidisciplinary management to address diagnosis, surgical timing, and psychological well‐being in disorder of sex ...
Maria Francesca Astorino, Serena Scalise, Chiara Di Bella, Maria Angela La Rosa, Basilia Piraino, Marco Calabrò, Mattia Gentile, Rosaria Maddalena Ruggeri, Emanuela Esposito, Silvana Briuglia, Salvatore Cannavò   +10 more
wiley   +1 more source

Detection of 46, XY Disorder of Sex Development (DSD) Based on Plasma Cell-Free DNA and Targeted Next-Generation Sequencing

, 2021
Mutations in the HSD17B3 gene cause HSD17B3 deficiency and result in 46, XY Disorders of Sex Development (46, XY DSD). The diagnosis of 46, XY DSD is very challenging and not rarely is confirmed only at older ages, when an affected XY female presents ...
Luigia De Falco, Rossana D’Angelo, Antonio Fico, Eloisa Evangelista, Roberto Sirica, Carmelo Piscopo, Ciro Scarpato, Raffaella Ruggiero, Giovanni Savarese, Teresa Suero, Antonella Di Carlo, Giulia Furino   +11 more
core   +1 more source

Variability in Sex Assignment at Birth and Etiological Diagnosis of Differences of Sex Development: A Ten-Year Institutional Experience from Assam

Indian Journal of Endocrinology and Metabolism
Introduction: Differences of sex development (DSD) also known as disorders of sex development encompass a wide spectrum of conditions with varying clinical presentations across different age groups. This study aims to analyse various aetiologies of DSD
Praveen Nagarajaiah, Ashok K Bhuyan, Abhamoni Baro, Uma K Saikia   +3 more
doaj   +1 more source

Categorization of differences of sex development among Egyptian children and the role of antimullerian hormone and inhibin B

Frontiers in Endocrinology, 2023
BackgroundDifferences of sex development (DSD) are congenital conditions linked to atypical development of chromosomal, gonadal, or anatomical sex.ObjectiveThe aim of this study was to demonstrate our experiences at the Diabetes Endocrine and Metabolism ...
Shereen Abdelghaffar, Engy Nasr AbdelMoneam, Samah A. Hassanein, Noha Abdelhalim Radwan, Marwa Farouk Mira   +4 more
doaj   +1 more source

Tailoring Differentiated Multiscale Microstructure to Enhance the Mechanical Properties of Additively Manufactured AlCoFeNi2 at Room and High Temperatures via Annealing

Rare Metals, Volume 45, Issue 4, April 2026.
ABSTRACT Additively manufactured AlCoFeNi series eutectic high‐entropy alloys (EHEAs) exhibit nonequilibrium dual‐phase microstructure in the as‐printed state, allowing them to be easily tailored through annealing to explore their strength–toughness potential.
Huidong Wu, Xinyu Zhang, Chunman Wang, Yi Ru, Lei Cao, Kaisheng Ming, Tao Dong, Ben Chen, Ming Gu, Xiang Wang, Wenqi Guo, Shusuo Li, Yanling Pei, Shengkai Gong   +13 more
wiley   +1 more source

Designer DNA‐Based Machines

SmartBot, Volume 2, Issue 1, March 2026.
DNA machinery represents a burgeoning frontier at the intersection of robotics and nanotechnology, evolving from static nanostructure toward dynamic nanorobots. Here, the authors review the comprehensive research pipeline of designer DNA‐based nanomachines, covering the design, analysis, and fabrication. These programmable systems enable transformative
Yiquan An, Fan Wu, Yanyu Xiong, Cheng Zhang, Jian S. Dai, Lifeng Zhou   +5 more
wiley   +1 more source

List of copy number variations of unclear clinical significance (UCS) in 46,XY DSD patients.

, 2013
List of copy number variations of unclear clinical significance (UCS) in 46,XY DSD patients.
Sung-Hae L. Kang (360379), Mounia Tannour-Louet (360374), Shuo Han (360375), Svetlana Yatsenko (360378), Lindsay Meyers (200200), Chad A. Shaw (94130), Jean-Francois Louet (360377), Sean T. Corbett (360376), Dolores J. Lamb (360380), Sau Wai Cheung (163977)   +9 more
core   +1 more source