Results 91 to 100 of about 2,568,206 (333)

The importance of temporal and spatial incoherence in quantitative interpretation of 4D-STEM

open access: yesUltramicroscopy, 2020
Recent developments in pixelated detectors, when combined with aberration correction of probe forming optics have greatly enhanced the field of scanning electron diffraction. Differential phase contrast is now routine and deep learning has been proposed as a method to extract maximum information from diffraction patterns. This work examines the effects
Mark P, Oxley, Ondrej E, Dyck
openaire   +3 more sources

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Unsupervised machine learning combined with 4D scanning transmission electron microscopy for bimodal nanostructural analysis

open access: yesScientific Reports
Unsupervised machine learning techniques have been combined with scanning transmission electron microscopy (STEM) to enable comprehensive crystal structure analysis with nanometer spatial resolution.
Koji Kimoto   +5 more
doaj   +1 more source

Grain Rotation and Crack Propagation in Bulge-Tested Gold Films with 4D-STEM

open access: yesJOM
This work investigates the stable crack propagation in notched, ultrafine-grained, freestanding Au films under cyclic loading with a bulge tester. Using intermittent transmission electron microscopy, including 4D scanning transmission electron microscopy,
David D. Gebhart   +5 more
semanticscholar   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang   +6 more
wiley   +1 more source

On the use of clustering workflows for automated microstructure segmentation of analytical STEM datasets

open access: yesAPL Materials
This study considers the issue of automated segmentation of scanning transmission electron microscopy (STEM) datasets using unsupervised machine learning approaches.
Zhiquan Kho   +5 more
doaj   +1 more source

Digit ratio (2D:4D) and male facial attractiveness: New data and a meta-analysis

open access: yes, 2013
Digit ratio (2D:4D) appears to correlate negatively with prenatal testosterone (T) effects in humans. As T probably increases facial masculinity, which in turn might be positively related to male facial attractiveness, a number of studies have looked ...
Honekopp, Johannes, Johannes Hönekopp
core   +1 more source

Neural crest-derived stem cells [PDF]

open access: yes, 2010
The neural crest is a transient embryonic structure in vertebrates that gives rise to most of the peripheral nervous system (PNS) and to several non-neural cell types, including smooth muscle cells of the cardiovascular system, pigment cells in the skin,
Sommer, L, Shakhova, O
core   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

Dielectrophoresis: A Review of Applications for Stem Cell Research [PDF]

open access: yes, 2010
Dielectrophoresis can discriminate distinct cellular identities in heterogeneous populations, and monitor cell state changes associated with activation and clonal expansion, apoptosis, and necrosis, without the need for biochemical labels.
De Sousa, Paul   +7 more
core   +1 more source

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