Results 111 to 120 of about 84,609,228 (161)

A cryptic plastid and a novel mitochondrial plasmid in <i>Leucomyxa plasmidifera</i> gen. and sp. nov. (Ochrophyta) push the frontiers of organellar biology. [PDF]

Open Biol
Barcytė D, Jaške K, Pánek T, Yurchenko T, Ševčíková T, Eliášová A, Eliáš M.   +6 more
europepmc   +1 more source

The GLYT1 inhibitor bitopertin mitigates erythroid PPIX production and liver disease in erythroid protoporphyria. [PDF]

J Clin Invest
Ducamp S, Wu M, Putra J, Campagna DR, Xiang Y, Hong V, Heeney MM, Dickey AK, Leaf RK, Fleming MD, MacDonald B, Schmidt PJ.   +11 more
europepmc   +1 more source

An extended network for regulation of heme homeostasis in cells. [PDF]

Proc Natl Acad Sci U S A
Gallio AE, Marson NA, Heesom KJ, Lewis PA, Alibhai D, Dugdale CA, Herman A, Basran J, Hudson AJ, Raven EL.   +9 more
europepmc   +1 more source

Milestones in the Elucidation of Heme Biosynthesis. [PDF]

Chem Rev
Dailey HA.
europepmc   +1 more source

An erythroid-specific lentiviral vector improves anemia and iron metabolism in a new model of XLSA.

Blood
Castruccio Castracani C, Breda L, Papp TE, Guerra A, Radaelli E, Assenmacher CA, Finesso G, Mui BL, Tam YK, Fontana S, Riganti C, Fiorito V, Petrillo S, Tolosano E, Parhiz H, Rivella S.   +15 more
europepmc   +1 more source

Murine models of erythroid 5ALA synthesis disorders and their conditional synthetic lethal dependency on pyridoxine.

Blood
Ducamp S, Sendamarai AK, Campagna DR, Chin DWL, Fujiwara Y, Schmidt PJ, Fleming MD.   +6 more
europepmc   +1 more source

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Diurnal Rhythm in Rat Liver 5‐Aminolevulinate Synthetase Activity

Biological Rhythm Research, 1980
Abstract 5‐Aminolevulinate synthetase activity was measured in livers of adult male rats by means of an improved assay. The enzyme exhibited a diurnal rhythm with a maximum during dark‐time. Inductions by allylisopropylacetamide during diurnal increase and decrease of enzyme activity resulted in the same amount of additionally formed enzyme.
W. Volknandt, R. Hardeland
exaly   +3 more sources

Trout (Salmo gairdneri R.) Liver 5-Aminolevulinate Synthetase: Subcellular Distribution and Properties

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1987
The subcellular distribution of trout liver 5-aminolevulinate synthetase has been studied. A cytosolic form of the enzyme has been found. Its activity was a 30% of the mitochondrial enzyme. The cytosolic form has a molecular weight of 110,000, larger than the mitochondrial enzyme (70,000). The two enzyme forms showed a pH optimum of 7.5.
O González
exaly   +4 more sources

Erythroid 5-aminolevulinate synthetase from trout (Salmo gairdneri R.)

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1986
A mitochondrial and cytosolic erythroid ALA-synthetase have been found in trout. The polypeptide existent in the cytosol is probably a precursor of the 90,000 mol. wt mitochondrial ALA-synthetase. The erythroid ALA-synthetase is about 20,000 mol. wt larger than the hepatic enzyme. The differences in mol.
J, Fernández, O, González, M, Martín, M, Ruiz Amil   +3 more
openaire   +3 more sources

Lack of Glucose Effect on the Induction of 5-Aminolevulinate Synthetase and Tyrosine Aminotransferase in the Isolated Perfused Rat Liver

Enzyme, 2017
In the isolated perfused rat liver, both 5-aminolevulinate synthetase and tyrosine aminotransferase were induced by the addition of 3.5 mmol/l allylisopropylacetamide and 58 μmol/l dexamethasone to the perfusion medium. Glucose (40 mmol/l) did not affect either the induction of these enzymes or the intrahepatic level of cyclic AMP.
K W, Bock, R, Weiner, J, Schultz
openaire   +3 more sources