Results 121 to 130 of about 690,096 (310)

Fibronectin1‐Expressing Subicular Circuits Selectively Govern the Retrieval of Novel Object Recognition

Advanced Science, EarlyView.
Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei, Jiaying Shi, Jing Xi, Yixiang Xu, Shuye Ying, Xukun Fan, Wangjialu Lu, Zhisheng Li, Menghan Li, Yu Wang, Li Cheng, Lin Yang, Lingyu Xu, Zhong Chen, Cenglin Xu, Yi Wang   +15 more
wiley   +1 more source

Barriers to Empowerment: Examining the Transition of Pakistani Women from Higher Education (HE) to Professional Life

Social Sciences
Gender equality is essential for economic and societal advancement, as outlined in the United Nations’ Sustainable Development Goal 5. This research examines the obstacles that hinder women’s progression from higher education to empowerment in Pakistan ...
Muhammad Qasim Rana, Angela Lee, Noreen Saher, Zeba Shabbir   +3 more
doaj   +1 more source

Agriculture, food security, nutrition and the Millennium Development Goals [In Arabic]: [PDF]

"...Today, 1.1 billion people live on less than one US dollar per day (the internationally recognized poverty threshold)—430 million in South Asia, 325 million in Sub-Saharan Africa, 260 million in East Asia and the Pacific, and 55 million in Latin ...
Rosegrant, Mark W., Swaminathan, Monkombu Sambasivan, von Braun, Joachim   +2 more
core  

Maternal Preconception Antibiotic Exposure Disrupts Microbial Succession: A Transgenerational Risk for Offspring Gut Mucosal Immaturity and Colitis Susceptibility

Advanced Science, EarlyView.
This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen, Ruqiao Duan, Cunzheng Zhang, Gaonan Li, XiaoLin Ji, Qi Zhang, Fei Pei, Kun Wang, Liping Duan   +8 more
wiley   +1 more source

Student attraction, persistence and retention in university STEM fields: successes and challenges

Cogent Education
As explicitly stated in SDG 5, STEM Education seeks gender equality. This study explores the impact of STEM on achieving gender equality and eliminating gender disparity in male and female enrollment and graduation from STEM-related fields in UAE ...
Ahmad Qablan, Hassan Tairab, Ahmed Alkaabi, Maxwell Opoku, Rachel Takriti   +4 more
doaj   +1 more source

Mapping Genetic Regulation of Transcription to Identify Functional Variants and Genes Associated with Pancreatic Cancer Risk

Advanced Science, EarlyView.
Integration of a pancreatic eQTL map with a GWAS meta‐analysis identifies 82 putative functional variants and 15 genes. The association between rs11102484 and pancreatic cancer risk is observed in a total of 5699 cases and 8467 controls. The G allele of rs11102484 weakens ZNF263 binding and the silencer‐promoter interaction, thereby increasing ST7L ...
Xiaoyang Wang, Hui Geng, Zhengyan Yao, Yuan Jiang, Can Chen, Zequn Lu, Shuangshuang Tian, Ming Zhang, Ruiyan Liu, Chenxi Feng, Bin Li, Xiaoping Miao, Jianbo Tian, Shaokai Zhang, Ying Zhu   +14 more
wiley   +1 more source

Agriculture, sécurité alimentaire, nutrition et les objectifs du Millénaire pour le Developpement: [PDF]

"...Today, 1.1 billion people live on less than one US dollar per day (the internationally recognized poverty threshold)—430 million in South Asia, 325 million in Sub-Saharan Africa, 260 million in East Asia and the Pacific, and 55 million in Latin ...
Rosegrant, Mark W., Swaminathan, Monkombu Sambasivan, von Braun, Joachim   +2 more
core  

Reduced Maintenance DNA Methylation Thresholds Enable Sensitive Reporter Assays for UHRF1 and DNMT1 Inhibition

Advanced Science, EarlyView.
The authors engineer colorectal cancer cells with reduced redundancy of UHRF1 and DNMT1, key DNA methylation maintenance factors, lowering the maintenance threshold and sensitizing cells to inhibition. They develop reporter assays driven by endogenous tumor‐suppressor gene promoters with enhanced sensitivity and dynamic range to demethylating drugs ...
Cuicui Xia, Ying Cui, Jiongliang Wang, Wenjing Bai, Danyang Wang, Yao Chen, Huahui Guo, Liangyi Zong, Bing Qin, Xintong Cai, Jie Wang, Jing Huang, Scott B. Rothbart, Zufeng Guo, Stephen B. Baylin, Xiangqian Kong   +15 more
wiley   +1 more source

What is gained when university leadership revisits and recommits to equality considering the 2030 Agenda for sustainable development

Feminismo/s
In 2015, all United Nations Member States adopted the 2030 Agenda for Sustainable Development, an ambitious initiative that aims to confront society’s biggest challenges in a decisive and coordinated fashion.
Idoia Fernández-Fernández, Estibaliz Saéz de Cámara, Leire Imaz   +2 more
doaj   +1 more source

Climate Action Impacts on Steelmaking Emissions of Persistent Organic Pollutants Highlight a Gap Between the Paris Agreement and the Stockholm Convention

Advanced Science, EarlyView.
Emissions of unintentionally produced persistent organic pollutants (UPOPs) and global warming are two major environmental challenges. But their governance has largely evolved in parallel, leaving the toxicity implications of climate‐driven industrial transitions poorly understood.
Yuxiang Sun, Qiuting Yang, Jianghui Yun, Yujue Yang, Junhao Tang, Qian Liu, Minghui Zheng, Guorui Liu   +7 more
wiley   +1 more source