Results 121 to 130 of about 9,896,464 (337)
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Determining dust temperatures and masses in the Herschel era: The importance of observations longward of 200 micron [PDF]
, 2010 Context. The properties of the dust grains (e.g., temperature and mass) can be derived from fitting far-IR SEDs (≥100 μm). Only with SPIRE on Herschel has it been possible to get high spatial resolution at 200 to 500 μm that is beyond the peak (~160 μm ...
Gordon, K. D., Reach, W. T.
core
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Internal marketing, collaboration and motivation in service quality management
, 1991 School of ...
Ballantyne, David
core
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Virtue Ethics, Corporate Sustainability, and Tax Disclosure: Evidence From Global Fortune 500 [PDF]
Chiara Mio +2 more
openalex +1 more source
Top Mass Measurement at CLIC at 500 GeV
, 2012 We present a study of the capability of a 500 GeV e+e- collider based on CLIC technology for precision measurements of top quark properties. The analysis is based on full detector simulations of the CLIC_ILD detector concept using Geant4, including ...
Poss, Stephane +2 more
core
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
The space environment - 100 to 500 kilometers [PDF]
Aeronomy study of nitrogen ultraviolet radiation from IBC 3 ...
Green, A. E. S.
core +1 more source