Invasive <i>Cunninghamella bertholletiae</i> Infections in children: a case series and literature review. [PDF]
Li X +9 more
europepmc +1 more source
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Conserved rod-to-spherical shape transitions in Escherichia coli through primordial experimental adaptations. [PDF]
Lu H +6 more
europepmc +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Comparison of urethane dimethacrylate monomer elution between indirect composites when subjecting to thermocycling. [PDF]
Hanifah NAM +5 more
europepmc +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Experimental Investigation into the Reactions Between Liquid Gallium and Inorganic Nitrogen Precursors (N<sub>2</sub>, NH<sub>3</sub>, and NH<sub>4</sub>Cl) at 400-500 °C. [PDF]
Zheng Y, Guan X.
europepmc +1 more source
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Effects of Ambient Oxygen Concentration on Microstructural Evolution and Mechanical Properties of Wire Arc Additively Manufactured Ti-6Al-4V Thin-Walled Components. [PDF]
Meng S +6 more
europepmc +1 more source

