Correction to Supporting Information for Li et al., Primed 3D injectable microniches enabling low-dosage cell therapy for critical limb ischemia. [PDF]
europepmc +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio+11 more
wiley +1 more source
Quality of life and retention in care among people living with HIV initiated on ART in the era of "Universal Test and Treat" policy at a large HIV Clinic in South Western Uganda. [PDF]
Tumuhairwe F+4 more
europepmc +1 more source
The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez+8 more
wiley +1 more source
Comparative analysis of the short-term germination and metal accumulation patterns of two Sorghum hybrids. [PDF]
Tőzsér D+7 more
europepmc +1 more source
Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim+3 more
wiley +1 more source
Enhancing schistosomiasis drug discovery approaches with optimized proteasome substrates. [PDF]
Silva EB+12 more
europepmc +1 more source
Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang+6 more
wiley +1 more source
Influence of Polyoxyethylene Stearyl Ether and Subsequent Annealing on n-Type Doping of CNT Yarns for Flexible Thermoelectric Generators. [PDF]
Heriyanto ADM+7 more
europepmc +1 more source