Results 71 to 80 of about 1,524,836 (233)
β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma
Advanced Science, EarlyView.β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto +20 more
wiley +1 more source
E-Journal of Chemistry, 2007 A procedure was developed for the determination of Sm, Eu and Yb in water samples by inductively coupled plasma-optical emission spectrometry (ICP-OES) after preconcentration on synthesized 5-(4-pyridyl azo)-8-quinolinol supported by Borassus flabellifer
J. Dilip Kumar +4 more
doaj +1 more source
Computer-aided proofs for multiparty computation with active security [PDF]
, 2018 Secure multi-party computation (MPC) is a general cryptographic technique that allows distrusting parties to compute a function of their individual inputs, while only revealing the output of the function.
Haagh, Helene +4 more
core +2 more sources
Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1
Advanced Science, EarlyView.Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang +10 more
wiley +1 more source
Inference on locally ordered breaks in multiple regressions [PDF]
, 2017 We consider issues related to inference about locally ordered breaks in a system of equations, as originally proposed by Qu and Perron (2007 Qu, Z., Perron, P. (2007). Estimating and testing structural changes in multivariate regressions. Econometrica 75:
Li, Ye, Perron, Pierre
core +1 more source
Advanced Science, EarlyView.CircMT‐RNR2 promotes wound healing by enhancing fibroblast proliferation, migration, contraction, and extracellular matrix (ECM) production. It sustains mitochondrial redox balance by stabilizing the antioxidant protein PRDX3, thereby reducing ROS‐induced damage. In diabetic foot ulcers, hypoxia, hyperglycemia, and reduced FGF2 and EGF expression lower
Guanglin Niu +13 more
wiley +1 more source
Pro‐ATO/Allicin Liposomes for Dual‐Pathway Targeting of p53‐Mutant Tumors
Advanced Science, EarlyView.Schematic illustration of the “pro‐ATO”/allicin liposomal strategy. Liposomal encapsulation improves the stability and bioavailability of both agents while masking allicin's odor. Upon release in the tumor microenvironment, ATO reactivates structural p53 mutants, and allicin inhibits ATR signaling while releasing H2S, collectively inducing synthetic ...
Xiaoling Xu +11 more
wiley +1 more source
Phytochemical-induced nucleolar stress results in the inhibition of breast cancer cell proliferation
Redox Biology, 2017 The nucleolus is a stress sensor and compromised nucleolar activity may be considered as an attractive anticancer strategy. In the present study, the effects of three plant-derived natural compounds, i.e., sulforaphane (SFN), ursolic acid (UA) and ...
Anna Lewinska +3 more
doaj +1 more source
An Investigation Study of the Image of a Nurse (3) : A Comparison of the Student's Image of a Nurse using the Longitudinal Method and the Cross-sectional Method [PDF]
, 2001 この研究の目的は,学生の看護婦イメージの縦断的研究法と横断的研究法による違いを調べることであった.調査対象者は,縦断的研究は78名,横断的研究は278名の看護学生である.調査は,1998年11月から2000年11月に行った.結果から以下のことがいえる.1)縦断的研究と横断的研究は同様の傾向を示した.2)看護婦イメージは,"知性"と"職業的魅力"の因子において,ポジティブな方向に変化した.3)この変化の理由は,学生のカリキュラムに関係があると考えられる.4)縦断的研究は,コホート要因を反映するので ...
502 +7 more
core +1 more source
Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome
Advanced Science, EarlyView.By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang +12 more
wiley +1 more source