Results 321 to 330 of about 1,768,342 (381)

Modernizing the FDA's 510(k) Pathway.

New England Journal of Medicine, 2019
Modernizing the FDA’s 510(k) Pathway More than 90% of FDA-reviewed devices enter the market by means of the 510(k) pathway. In September 2019, the FDA finalized reforms to the pathway.
V. Rathi, J. Ross
semanticscholar   +3 more sources

Preclinical Evaluation of CD36-Targeting Antiangiogenic Peptide ABT-510 for Near-Infrared Fluorescence Molecular Imaging of Colorectal Cancer.

Analytical Chemistry, 2023
Surgical resection constitutes the first choice of treatment for colorectal cancer (CRC). Despite advancements in intraoperative navigation, there remains a considerable lack of effective targeting probes for the imaging-guided surgical navigation of CRC
Ping Luo, Kuncheng Zhou, Gang Li, Tianming Tao, Ji Tao, Ray P. S. Han, Yuanbiao Tu   +6 more
semanticscholar   +1 more source

Case report 510

Skeletal Radiology, 1988
This 26-year-old white man complained of a dull ache in the hip over a 4-months period. There was no history of trauma, unusual athletic activity, vigorous massage, or other cause of local contusion was obtained. He had experienced no fever or weight loss. Physical examination revealed a tender mass measuring approximately 5 x 5 cm anterior to the left
Andrew E. Rosenberg, Jasvir S. Khurana, Daniel I. Rosenthal, Shigeru Ehara   +3 more
openaire   +2 more sources

Phase 1 study evaluating the safety, tolerability, pharmacokinetics (PK), and efficacy of AMG 510, a novel small molecule KRASG12C inhibitor, in advanced solid tumors.

Journal of Clinical Oncology, 2019
3003 Background: The KRASG12C mutation is found in approximately 13% of lung adenocarcinomas and 1–3% of other solid tumors, but there is no approved therapy that targets this mutation. AMG 510 is a novel small molecule that specifically and irreversibly
M. Fakih, B. O'Neil, T. Price, G. Falchook, J. Desai, J. Kuo, R. Govindan, E. Rasmussen, P. K. Morrow, J. Ngang, H. Henary, D. Hong   +11 more
semanticscholar   +1 more source

CircRNA SCARB1 promotes renal cell carcinoma progression via miR-510-5p/SDC3 axis.

Current Cancer Drug Targets, 2020
BACKGROUND Emerging studies have indicated that circular RNAs (circRNAs) play important roles in the development of many tumors. CircRNA-scavenger receptor class B member 1 (Circ-SCARB1) was consistently reported as an elevated circRNA in RCC tissues ...
Jijian Sun, Shijie Pan, Hong Cui, Hao Li
semanticscholar   +1 more source

Step site adsorption and ordering of CO on Ni(510) and Pd(510)

Surface Science, 1996
Using HREELS and LEED we have observed profound differences in step site adsorption and ordering of CO on two stepped fcc (100) surfaces, Ni(510) and Pd(510). On Ni(510) we find that CO initially decorates the steps. This seems to prohibit the formation of any globally ordered structure, although the local structure at high coverages resembles that ...
Krister Svensson, I Rickardsson, Stefan Andersson, C. Nyberg   +3 more
openaire   +2 more sources

Malrotation of the McGhan Style 510 Prosthesis

Plastic and Reconstructive Surgery, 2010
Anatomically shaped cohesive silicone breast implants are frequently used in aesthetic and reconstructive surgery. After successful results with the Style 410 prosthesis, McGhan (Natrelle, Allergan) introduced the Style 510 prosthesis. After using this novel prosthesis, the authors encountered a high number of prosthesis malrotations on self-reported ...
Schots, J.M., Fechner, M.R., Hoogbergen, M.M., Tits, H.W.H.J.   +3 more
openaire   +3 more sources

CodeBreak 100: Activity of AMG 510, a novel small molecule inhibitor of KRASG12C, in patients with advanced colorectal cancer.

, 2020
4018Background: Kirsten rat sarcoma viral oncogene homolog (KRAS) p.G12C mutation is associated with poor prognosis in colorectal cancer (CRC).
M. Fakih, J. Desai, Y. Kuboki, J. Strickler, T. Price, G. Durm, G. Falchook, C. Denlinger, J. Krauss, G. Shapiro, Tae Won Kim, Keunchil Park, A. Coveler, P. Munster, Bob T. Li, June Kim, H. Henary, G. Ngarmchamnanrith, D. Hong   +18 more
semanticscholar   +1 more source

What's in a 510(k)? [PDF]

IEEE Engineering in Medicine and Biology Magazine, 2003
If you hope to market a new medical device in the United States, sending a premarket notification, or 510(k) is probably the easiest and fastest way to do so. The article briefly looks at the 510(k) and outlines what it is, gives guidelines for preparing it including useful resources, and gives an idea of fees and review time required.
openaire   +1 more source

Minnesota Agricultural Economist No. 510

1968
Statewide Water Resource Planning in Minnesota; Joint Products of Natural ...
Waelti, John J., Martin, Lee R., Waelti, John J., Martin, Lee R.   +3 more
openaire   +3 more sources