Results 171 to 180 of about 24,557 (225)
Stima della massa del buco nero al centro della galassia lenticolare NGC 5141
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Abstract 5141: Optimizing peptide-drug conjugate delivery as an alternative to antibody-drug conjugates for solid tumors [PDF]
Cancer Research, 2017 Abstract Antibody-drug conjugates (ADCs) have been FDA approved for targeted delivery of chemotherapy to a small subset of cancers. However, there are significant limitations in their clinical utility in the majority of cancers: despite hundreds of clinical trials, there are only two FDA approved drugs currently on the market.
Theo L. Sottero +3 more
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Abstract 5141: GenomeSpace: an environment for frictionless bioinformatics.
Cancer Research, 2013Abstract Over the past several years, cancer genome characterization initiatives such as The Cancer Genome Atlas, International Cancer Genome Consortium, and the Tumor Sequencing Project have produced an explosion of genomic data. The pace of data production has increased with the adoption of next-generation sequencing technologies and ...
Michael Reich +6 more
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Cancer Research, 2023
Abstract Introduction: While the prognostic value of immune system biomarkers has been well explored, role of cancer associated macrophages in bladder cancer(BC) is unclear due to lack of consistent results, coupled with tissue nonspecific transcriptomic signature.
Laura Bukavina +12 more
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Abstract Introduction: While the prognostic value of immune system biomarkers has been well explored, role of cancer associated macrophages in bladder cancer(BC) is unclear due to lack of consistent results, coupled with tissue nonspecific transcriptomic signature.
Laura Bukavina +12 more
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Cancer Research, 2022
Abstract The promise of precision medicine in oncology is to identify the ideal treatment for each patient, eliminating failed treatment cycles and reducing treatment burdens on patients and payors. While gene sequencing can predict effective treatment options in some cases, studies have estimated that only 10-15% of cancer patients are ...
Jonathan Scolnick +4 more
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Abstract The promise of precision medicine in oncology is to identify the ideal treatment for each patient, eliminating failed treatment cycles and reducing treatment burdens on patients and payors. While gene sequencing can predict effective treatment options in some cases, studies have estimated that only 10-15% of cancer patients are ...
Jonathan Scolnick +4 more
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Cancer Research, 2010
Abstract Aggressive metastatic neuroblastoma confers a poor clinical prognosis. Stathmin is a microtubule destabilizing protein highly expressed in advanced stage (metastatic) neuroblastoma (1) that promotes metastasis of non-neuronal cancers (2). However, stathmin's role in neuroblastoma metastasis is unclear.
Frances L. Byrne +2 more
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Abstract Aggressive metastatic neuroblastoma confers a poor clinical prognosis. Stathmin is a microtubule destabilizing protein highly expressed in advanced stage (metastatic) neuroblastoma (1) that promotes metastasis of non-neuronal cancers (2). However, stathmin's role in neuroblastoma metastasis is unclear.
Frances L. Byrne +2 more
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Cancer Research, 2015
Abstract There has been longstanding interest in the relationship between the immune system and malignant melanoma, the deadliest form of skin cancer. Melanoma has been the tumor of choice for the evaluation of a wide variety of therapeutic approaches that rely on stimulation of the immune system to combat cancer.
Katrina M. Meeth +2 more
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Abstract There has been longstanding interest in the relationship between the immune system and malignant melanoma, the deadliest form of skin cancer. Melanoma has been the tumor of choice for the evaluation of a wide variety of therapeutic approaches that rely on stimulation of the immune system to combat cancer.
Katrina M. Meeth +2 more
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