Results 1 to 10 of about 153,539 (205)

A novel orally active HDAC6 inhibitor T-518 shows a therapeutic potential for Alzheimer’s disease and tauopathy in mice

Scientific Reports, 2021
Accumulation of tau protein is a key pathology of age-related neurodegenerative diseases such as Alzheimer's disease and progressive supranuclear palsy. Those diseases are collectively termed tauopathies.
T. Onishi, Ryouta Maeda, Michiko Terada, Sho Sato, T. Fujii, M. Ito, Kentaro Hashikami, T. Kawamoto, Maiko Tanaka   +8 more
semanticscholar   +1 more source

hsa-miR-518-5p/hsa-miR-3135b Regulates the REL/SOD2 Pathway in Ischemic Cerebral Infarction

Frontiers in Neurology, 2022
Objectives Ischemic cerebral infarction (ICI) is a fatal neurovascular disorder. A bioinformatics approach based on single-cell and bulk RNA-seq analyses was applied to investigate the pathways and genes involved in ICI and study the expression profile ...
Boyan Zhao, Xiaofan Jiang
semanticscholar   +1 more source

Secondary Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus (HP-PRRSV2) Infection Augments Inflammatory Responses, Clinical Outcomes, and Pathogen Load in Glaesserella-parasuis-Infected Piglets

Veterinary Sciences, 2023
Glaesserella parasuis (Gps), Gram-negative bacteria, are a universal respiratory-disease-causing pathogen in swine that colonize the upper respiratory tract.
Zhixin Guan, Linlin Pang, Yan Ouyang, Yifeng Jiang, Junjie Zhang, Yafeng Qiu, Zongjie Li, Beibei Li, Ke Liu, Donghua Shao, Zhiyong Ma, Jianchao Wei   +11 more
doaj   +1 more source

Token Merging: Your ViT But Faster [PDF]

International Conference on Learning Representations, 2022
We introduce Token Merging (ToMe), a simple method to increase the throughput of existing ViT models without needing to train. ToMe gradually combines similar tokens in a transformer using a general and light-weight matching algorithm that is as fast as ...
Daniel Bolya, Cheng-Yang Fu, Xiaoliang Dai, Peizhao Zhang, Christoph Feichtenhofer, Judy Hoffman   +5 more
semanticscholar   +1 more source

Explorando internet de las cosas basado en ESP8266: herramientas y caso de estudio

Revista de Ciencias Tecnológicas, 2023
El presente proyecto se centra en la exploración del internet de las cosas basado en ESP8266 con el desarrollo de una aplicación para dispositivos móviles que integra el control y monitoreo de un alimentador automático de mascotas. El documento presenta
Elva Lilia Reynoso Jardón, Manuel de Jesús Nandayapa Alfaro, Quirino Estrada Barbosa , Raul Ñeco Caberta , Meilynn Jeyli Pineda Gugenbuhul, José Alfredo Ramirez Monares, José Francisco Arvizu Astorga   +6 more
doaj   +1 more source

Safety and Efficacy Evaluation of Recombinant Marek’s Disease Virus with REV-LTR

Vaccines, 2020
Recently, chickens vaccinated with the CVI988/Rispens vaccine showed increased tumor incidence. Moreover, many strains of Marek’s disease virus (MDV) that were naturally integrated with the long terminal repeat (LTR) of the avian reticuloendotheliosis ...
Cuiping Song, Yang Yang, Jing Hu, Shengqing Yu, Yingjie Sun, Xvsheng Qiu, Lei Tan, Chunchun Meng, Ying Liao, Weiwei Liu, Chan Ding   +10 more
doaj   +1 more source

Epidemiological Features and Clinical Repercussions of Supernumerary Teeth in a Multicenter Study: A Review of 518 Patients with Hyperdontia in Spanish Population

European Journal of Dentistry, 2020
Objectives The aim of this study was to establish the prevalence of supernumerary teeth (ST) in a sector of the population of Madrid, as well as possible complications associated with the presence of these teeth.
J. C. Brinkmann, N. Martínez-Rodríguez, M. Martín-Ares, J. Sanz-Alonso, J. Marino, M. J. Suárez García, C. B. Dorado, J. Martínez-González   +7 more
semanticscholar   +1 more source

Asteroseismological analysis of the ultra-massive ZZ Ceti stars BPM 37093, GD 518, and SDSS J0840+5222 [PDF]

Astronomy & Astrophysics, 2019
Context. Ultra-massive (≳1 M⊙) hydrogen-rich (DA) white dwarfs are expected to have a substantial portion of their cores in a crystalline state at the effective temperatures characterising the ZZ Ceti instability strip (Teff ∼ 12 500 K) as a result of ...
A. C'orsico, F. D. Ger'onimo, M. Camisassa, L. Althaus   +3 more
semanticscholar   +1 more source

Clutter Suppression Algorithm with Joint Intrinsic Clutter Motion Errors Calibration and Off-Grid Effects Mitigation in Airborne Passive Radars

Applied Sciences, 2023
In an airborne passive radar, multipath (MP) clutter, which is caused by MP signals contained in the contaminated reference signal, degrades the space-time adaptive processing (STAP) performance.
Yaqi Deng, Zhengwang Pei, Wenguo Li, Dongchu Jiang   +3 more
doaj   +1 more source

MicroRNA-518-3p suppresses cell proliferation, invasion and migration in colorectal cancer via targeting TRIP4.

Biochemistry and cell biology = Biochimie et biologie cellulaire, 2020
MicroRNA (miR)-518-3p has been shown to function as a tumor suppressor. The present study was undertaken to investigate the effects of miR-518-3p in colorectal cancer (CRC).
H. Yang, Jia-Hui Ren, Yu Bai, Jielin Jiang, Shiyao Xiao   +4 more
semanticscholar   +1 more source