Results 91 to 100 of about 213,740 (238)

The Impact of miR-21-5p, miR-145-5p and miR-382-5p Expression in Gastric Adenocarcinoma Cells on Lymphatic Spread Capability

open access: yesBiomedicines
Objectives: miR-21-5p, miR-145-5p and miR-382-5p have been associated with angiogenesis, which plays a central role in tumor growth and metastasis formation.
Maciej Ciesielski   +8 more
doaj   +1 more source

Dose‐related propofol resistance in COVID‐19 patients: Altered drug plasma levels, mechanistic insights from neuronal‐derived extracellular vesicles and miRNA analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Critical care for COVID‐19 patients presents unique challenges, particularly in sedation management. Patients demonstrate notable dose‐related resistance to propofol, potentially due to complex pharmacokinetic alterations. Emerging evidence suggests that plasma extracellular vesicle‐associated miRNA represents valuable predictive ...
Debora Curci   +10 more
wiley   +1 more source

Integrating chemo‐mechanical cues in nano‐microscale environments for stem cell regulation

open access: yesBMEMat, EarlyView.
Nano/microscale control strategies, including nano/microscale materials, ligand spacings, and cell encapsulating gels, cell mechanics, integrin signaling, and biochemical cues to direct stem cell fate, tissue regeneration, and organoid engineering, enabling advanced biomedical applications through mechanoregulation at cell‐material interfaces ...
Rajendra K. Singh   +5 more
wiley   +1 more source

Stakeholder Engagement as a Design Principle: Orchestrating a Digital Platform for the Safety and Sustainability of the Nanomaterials Sector

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT The governance of chemicals and nanomaterials presents a critical challenge, as significant uncertainties regarding safety and sustainability match their innovation potential. This creates a “knowledge‐to‐action” gap, hindering the practical implementation of safety and sustainability by design (SSbD) principles.
Mario Miozza   +4 more
wiley   +1 more source

Dark god of Parnassa, tablet concordance KBo II 8 - CTH 519

open access: yes, 2015
Transcription of the inventory related to the 'dark god' of Parnassa based on tablet concordance KBo II 8 (inventory no. Bo 11). Emmanuel Laroche translated this text as "Le "dieu noir" de Parnassa,” and classified the concordance in the category of ...
Gonnet-Bağana, Hatice
core   +1 more source

JTV-519 Japan tobacco

open access: yes, 2001
Japan Tobacco is developing the mixed action ion channel blocker, JTV-519, which has potential use as an antiarrhythmic. The drug is a novel cardioprotectant derivative of 1,4-benzothiazepine for which phase I trials were completed in the third quarter ...
Tse, HF, Lam, WF
core  

Corporate Decarbonization: Understanding CO2 Emission Drivers Across High‐ and Low‐Polluting Firms in OECD Countries

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Decarbonization of the economy is a central challenge in the fight against climate change. Although most governments show clear commitment to limiting global warming, the drivers of corporate decarbonization remain underexplored. Using a dataset of 1052 firms from OECD, this article analyses how intangible assets and environmental innovation ...
Yanik Nimtz, Mercedes Teruel
wiley   +1 more source

Financing Climate Action Through Fair Taxation: How SDG Engagement Reduces Corporate Tax Avoidance

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT The transition to a low‐carbon economy, central to achieving Paris Agreement targets and Sustainable Development Goal 13 (Climate Action), requires unprecedented public and private investment. A significant climate financing gap persists, however, exacerbated by corporate practices that erode the public revenue base.
Ahmed Aboud   +3 more
wiley   +1 more source

Band 5, 519 (Sammlung Friedlaender)

open access: yes
BAND 5, 519 (SAMMLUNG FRIEDLAENDER) Band 5, 519 (Sammlung Friedlaender) (Public Domain ...

core  

Do High Temperatures Affect Firm Demography? Evidence From Italy

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT This study analyses the impact of high temperatures and heat stress on Italian firm demography during 2009–2022. Combining provincial‐firm‐level data with a high‐resolution multidecadal meteorological dataset, we investigate whether high temperatures—absolute and anomalous—affect firm entry and exit rates.
Concetta Carnevale   +3 more
wiley   +1 more source

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