Results 71 to 80 of about 1,409,420 (284)

High‐Content SRS Imaging Unveils Altered Cholesterol Metabolism in Ovarian Cancers Under CAR‐T Treatment

Advanced Science, EarlyView.
High‐content Stimulated Raman Scattering (SRS) Imaging reveals that ovarian cancer cells surviving Chimeric Antigen Receptor (CAR) ‐T cell challenge exhibit increased cholesterol esterification. Pharmacological inhibition of this pathway with Avasimibe significantly enhances CAR‐T induced killing of ovarian cancer cells by reducing cancer cell ...
Chinmayee V. Prabhu Dessai, Zhuoying Huang, Haonan Lin, Guangrui Ding, Hongjian He, Menna Siddiqui, Meng Zhang, Wilson Wong, Ji‐Xin Cheng   +8 more
wiley   +1 more source

Determination of 5-Hydroxymethylfurfural and Saccharides in Mead

Kvasný průmysl, 2018
This work is focused on determination of 5-hydroxymethylfurfural (HMF), glucose, fructose and sucrose in meads. Reversed-phase high performance liquid chromatography with spectrophotometric detection was used for the separation of HMF.
Miroslava Juričová, Soňa Řezková, Kamila Moravcová, Jan Fisher, Lenka Česlová   +4 more
doaj   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Interfacial mechanisms involved in the interaction between Fusarium oxysporum f. sp. albedinis and date palm root

Journal of Crop Protection, 2021
Our study aims to evaluate the physicochemical mechanism involved in the adhesion of Fusarium oxysporum f. sp. albedinis (Foa) on date palm root of resistant (Aziza M) and susceptible (Boufegouss) varieties by determining their surface properties ...
Souad Lekchiri, Taoufik Hakim, Hafida Zahir, Redouane Benabbes, Kaoutar El Fazazi, Chorouk Zanane, Abdeslam Jaafari, Mostafa ELLouali, Hassane Latrache   +8 more
doaj  

Surface‐Bound Superoxide Radical‐Mediated Photo‐Fenton Mineralization of Ciprofloxacin on Fe‐Sillenite Nanosheets

Advanced Science, EarlyView.
This study systematically compares the degradation efficiency of CIP in a H2O2‐alone system and a novel Bi12FeO20‐H2O2 photo‐Fenton system. It reveals for the first time the presence of a quinone‐imine intermediate in the H2O2‐alone system, which exhibits toxicity comparable to CIP.
Wenting Qiu, Ji Liu, Hengjun Shang, Yaning Zhang, Shuai Dou, Jing Xu, Ying Zhang, Yang Lou, Yongfa Zhu, Chengsi Pan   +9 more
wiley   +1 more source

Quantum Coins [PDF]

, 2009
One of the earliest cryptographic applications of quantum information was to create quantum digital cash that could not be counterfeited. In this paper, we describe a new type of quantum money: quantum coins, where all coins of the same denomination are ...
Mosca, Michele, Stebila, Douglas
core   +3 more sources

Record‐High Performance Hyperfluorescent OLEDs Achieved via Electronic Structure Control of Chlorine‐Diversified MR‐TADF Emitters

Advanced Science, EarlyView.
A late‐stage diversification strategy for the benchmark MR‐TADF emitter ω‐DABNA enables precise electronic structure control via chlorine‐activated functionalization. The resulting derivatives achieve tunable emission from 523 to 533 nm with record‐high EQE1000 up to 34.0% and excellent color purity (CIEy = 0.70–0.73), establishing a versatile platform
Taehwan Lee, Junki Ochi, Shigetada Uemura, Feiran Liu, Jiping Hao, Yasuhiro Kondo, Masahiro Hayakawa, Takuji Hatakeyama   +7 more
wiley   +1 more source

Synthesis and characterization of cis-bisdiphenylphosphinoethene gold(I) complexes

Comptes Rendus. Chimie
A series of solid-state structures of gold(I) complexes using the semi-rigid cis-1,2- bis(diphenylphosphino)ethene (= cis-bdppe) ligand are reported. The proximity of the phosphine donor atoms of the bidentate ligand framework greatly favors formation of
Fayet, Océane Yvonne Odette, Crespi, Stefano, Orthaber, Andreas   +2 more
doaj   +1 more source

Transcriptomic and Neuroimaging Decoding of Brain‐Immune Crosstalk in Thyroid Eye Disease

Advanced Science, EarlyView.
This study employed an imaging transcriptomics framework integrating resting‐state fMRI with Allen Human Brain Atlas transcriptomic data, coupled with peripheral blood RNA sequencing, to decode brain‐immune crosstalk in thyroid eye disease. Frontal, parietal, subcortical, and brainstem regions were identified as key neuroimmune‐ vulnerable regions ...
Haiyang Zhang, Yuting Liu, Shufan Jiang, Zilin Fang, Mengda Jiang, Xiaofeng Tao, Tianyi Zhu, Jipeng Li, Sijie Fang, Xuefei Song, Yinwei Li, Jing Sun, Chuanjun Tong, Zhengrun Gao, Huifang Zhou, Xianqun Fan   +15 more
wiley   +1 more source

Associations between APOE‐TOMM40 ‘523 haplotypes and limbic system white matter microstructure

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
INTRODUCTION We assessed associations between apolipoprotein E Translocase of Outer Mitochondrial Membrane 40 (APOE‐TOMM40)‐‘523 haplotypes and white matter microstructure (WMM) across limbic tracts important for memory and cognition in non‐Hispanic ...
Katelyn E. Mooney, Derek B. Archer, Aditi Sathe, Timothy J. Hohman, Ose Kadiri, Melissa Lamar, Konstantinos Arfanakis, Lei Yu, Lisa L. Barnes, Kacie D. Deters   +9 more
doaj   +1 more source