Results 51 to 60 of about 5,127 (118)

Design and Synthesis of Novel Imidazo[4,5‐c]pyridine Derivatives, Evaluation of Their Activity Against Hepatitis C Virus and In Silico Prediction of Their Binding Mode to NS4B Protein

ChemMedChem, Volume 21, Issue 13, 14 July 2026.
A series of 18 novel imidazo[4,5‐c]pyridines was synthesized, and their anti‐HCV activity was evaluated. Compound 30b was identified as the most promising one, with EC50 = 6.61 µM. Molecular docking studies indicated the NS4B protein of the HCV as a potential target of these derivatives.
Eftychia Karampella, George Mpekoulis, Maria Georgiou, Iris Kolida, Katerina I. Kalliampakou, Eirini P. Kollia, Eleni V. Mikropoulou, Maria Halabalaki, Christos T. Chasapis, Niki Vassilaki, Nikolaos Lougiakis   +10 more
wiley   +1 more source

Integrating Backscattered Electron Imaging and Multi-Feature-Weighted Clustering for Quantification of Hydrated C₃S Microstructure

Buildings
The microstructure of cement paste is governed by the hydration of its major component, tricalcium silicate (C3S). Quantitative analysis of C3S microstructural images is critical for elucidating the microstructure-property correlation in cementitious ...
Xin Wang, Yongjun Luo
doaj   +1 more source

In Situ Hybridization Status of 568 Cases of HER2 Equivocal Breast Cancer

Zhongliu Fangzhi Yanjiu, 2019
Objective To compare the differences between 2013 and 2018 ASCO/CAP HER2 testing guidelines in 568 immunohistochemical HER2 equivocal breast cancer patients and to analyze the accuracy and deficiency of dual-color silver enhanced in-situ hybridization ...
JIANG Yi'na, WANG Bo, ZHOU Can, WANG Hongyan   +3 more
doaj   +1 more source

Severe Postpartum Hemorrhage After Vaginal Delivery in an Osteogenesis Imperfecta Type I Patient: A Case Report

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Pregnant patients with osteogenesis imperfecta type I are at increased risk of obstetric and hemorrhagic complications. Early multidisciplinary planning and anesthesiology involvement are essential. Severe postpartum hemorrhage may result from uterine atony and tissue fragility, requiring prompt uterotonic therapy, surgical intervention, blood
Madeline Dow, Aariya Srinivasan, Sabry Ayad   +2 more
wiley   +1 more source

Incidencia, diagnóstico histopatológico y pronóstico de tumores periampulares tratados quirúrgicamente. Hospital Sabogal - EsSalud, 2004-2012

Revista de la Facultad de Medicina Humana, 2017
Introducción. Los Tumores periampulares corresponden a un grupo heterogéneo de neoplasias ubicados en la región anatómica que da su nombre, cobra importancia en los últimos años por su incidencia ascendente. Objetivo.
Rolando Percy Zela Campos
doaj   +1 more source

Improving the Quality of Wheat Flour Bread by a Thermophilic Xylanase with Ultra Activity and Stability Reconstructed by Ancestral Sequence and Computational-Aided Analysis

Molecules
Xylanase is an essential component used to hydrolyze the xylan in wheat flour to enhance the quality of bread. Presently, cold-activated xylanase is popularly utilized to aid in the development of dough.
Guoshuai Hu, Xizhi Hong, Meixin Zhu, Lei Lei, Zhenggang Han, Yong Meng, Jiangke Yang   +6 more
doaj   +1 more source

RF linearity and improved transconductance of ScAlN/GaN HEMT with novel inverse L-shaped gate structure

Results in Physics
In this study, we investigate the enhancement of effective transconductance and gain linearity in submicrometer gate AlGaN-barrier-based transistors utilizing ScAlN/GaN coupling-channel structures.
Zhen Liu, Huiqing Sun, Longfei Yang, Ruipeng Lv, Yuanhao Zhang, Yuan Li, Yong Huang, Zhiyou Guo   +7 more
doaj   +1 more source

Assessment Of Bronchoalveolar Lavage Cytology in Rheumatoid Arthritis Patients: analytical cross-sectional study.

Arcades of Medicine
: Background Rheumatoid arthritis (RA) is a chronic inflammatory disease where lung involvement, like interstitial lung disease (ILD), increases morbidity. Bronchoalveolar lavage (BAL) cytology helps analyze lung inflammation.
Abdelrahman Gaber, aya abdeldaym, mohamed Hasswa, Abdelmoneim Hamed   +3 more
doaj   +1 more source

Widespread and strong impacts of river fragmentation by anthropogenic barriers on fishes in the Mekong River Basin

Communications Earth & Environment
The Mekong River, a global freshwater biodiversity hotspot, has suffered from intensive barrier construction, resulting in major challenges in safeguarding its fauna.
Jingrui Sun, Damiano Baldan, Martyn C. Lucas, Jie Wang, Amaia A. Rodeles, Shams M. Galib, Juan Tao, Mingbo Li, Daming He, Chengzhi Ding   +9 more
doaj   +1 more source

Production of Different Mushroom Protein Hydrolysates as Potential Flavourings in Chicken Soup Using Stem Bromelain Hydrolysis

Food Technology and Biotechnology, 2019
The pleasant taste of edible mushrooms, which is attributed to their high protein content, makes them an attractive source for the production of protein hydrolysates with good taste properties. In the present work, different mushroom protein hydrolysates
San-San Ang, Mohammad Rashedi Ismail-Fitry   +1 more
doaj   +1 more source