Results 221 to 230 of about 233,265 (291)
Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier
SETD2 ablation causes dysregulation and recruitment defects of ribosome biogenesis factors, resulting in translational disorders of barrier maintenance genes, thereby compromising the intestinal barrier. These findings unveil a previously unappreciated role of ribosome biogenesis and translational regulation in preserving the intestinal epithelial ...
Hanyu Rao +11 more
wiley +1 more source
The Optimal Exercise Modality and Dose for Cortisol Reduction in Psychological Distress: A Systematic Review and Network Meta-Analysis. [PDF]
Li X, Huang J, Zhu F.
europepmc +1 more source
This work shows, for the first time, that the stereocilia membrane in cochlear hair cells is dynamically regulated by the mechanotransduction channel to impact the membrane mechanical properties. This work provides direct evidence that the opening and closing associated with the MET channel is regulating the membrane viscosity suggesting that the MET ...
Shefin S. George, Anthony J. Ricci
wiley +1 more source
Stabilized Ion Selectivity Corrects Activation Drift in Kalium Channelrhodopsins
As newly emerged optogenetic tools, potassium channelrhodopsins (KCRs) can drift from inhibition to activation during illumination as K⁺ selectivity declines. It is shown that both the absolute K⁺/Na⁺ permeability ratio and its stability over time govern this drift, identify KCR1‐C29D as a reliably inhibitory variant, and outline design principles for ...
Xiao Duan +14 more
wiley +1 more source
Phenotypes of Food Allergies in Patients with Atopic Dermatitis Aged Under 24 Months: A Multicenter Study. [PDF]
Cogurlu MT +33 more
europepmc +1 more source
This study identifies the SOX9/TIMP1 axis as a key regulator of immune evasion in gastric cancer. iRGD‐conjugated nanoparticles co‐delivering si‐SOX9, Ce6, and L‐Arg are developed to synergize with photodynamic therapy. The nanoplatform suppresses tumor growth, promotes dendritic cell maturation, and enhances CD8+ T‐cell activation, offering a ...
Banghua Zhong +3 more
wiley +1 more source
Esterase and Peroxidase Are Involved in the Transformation of Chitosan Films by the Fungus <i>Fusarium oxysporum</i> Schltdl. IBPPM 543. [PDF]
Pozdnyakova NN +6 more
europepmc +1 more source

