Results 291 to 300 of about 1,643,403 (372)

Adaptive Antioxidant Nanomedicines Inhibit Ferroptosis in Renal Tubular Epithelial Cells to Alleviate Diabetic Kidney Disease

Advanced Science, EarlyView.
In this study, an adaptive antioxidant nanodrug (AAN) is developed through the self‐polymerization of L‐selenocysteine. The AAN exhibits dual functionalities: antioxidant activity (scavenging reactive oxygen species) and mitochondrial targeting. Moreover, the released selenium (Se) participates in the synthesis of glutathione peroxidase 4 (GPX4), which
Zerun Liu, Ting Huang, Ying Hong, Yuqi Yang, Wensheng Chen, Qingtao Zeng, Qiaohui Chen, Yongqi Yang, Xiaohong Ying, Wan Zeng, Ziyu Wu, Tianjiao Zhao, Xuesi Wan, Jianlin Chen, Kelong Ai, Qiong Huang   +15 more
wiley   +1 more source

Development and validation of machine learning-based risk prediction models for ICU-acquired weakness: a prospective cohort study. [PDF]

Eur J Med Res
Zhang Y, Wang Y, Yang J, Li Q, Zhou M, Lu J, Hu Q, Ma F.   +7 more
europepmc   +1 more source

Acidosis Forces Fatty Acid Uptake and Metabolism in Cancer Cells Regardless of Genotype

Advanced Science, EarlyView.
This study demonstrates that biological acidosis, commonly observed in tumors and ischemic conditions, actively promotes the protonation of fatty acids, thereby facilitating the uptake of their neutral forms. Consequently, the preference for lipid metabolism in acid‐exposed cells does not arise from genetic reprogramming that prioritizes lipids as the ...
Sébastien Ibanez, Maria Virginia Giolito, Sultan Al‐Siyabi, Kristian Serafimov, Florine Laloux, Emeline Dierge, Léo Aubert, Céline Guilbaud, Selena Kaye, Paula Varon, Dorothée Marchand, Hanne Vlieghe, Emmanuel Hermans, Caroline Bouzin, Davide Brusa, Christiani Andrade Amorim, Barabara Pachikian, Yvan Larondelle, Cyril Corbet, Chantal Dessy, Olivier Feron   +20 more
wiley   +1 more source

ON-OFF nanopores for optical control of transmembrane ionic communication. [PDF]

Nat Nanotechnol
Wang X, Kerckhoffs A, Riexinger J, Cornall M, Langton MJ, Bayley H, Qing Y.   +6 more
europepmc   +1 more source

Pulsed Laser Synthesis of Carbon Nanostructures from Organic Molecular Liquids: Structure, Kinetics and Photophysical Properties

Advanced Science, EarlyView.
The non‐focused nanosecond pulsed laser irradiation of aromatic liquids produces amorphous carbon nanodots (CNDs) or curved‐graphene quantum dots (c‐GQDs) by surface‐catalyzed 0‐order reactions under kinetic control. C hybridization partially changes from sp2 to sp3. O‐based groups passivate the surface.
Antonio Ribeiro‐González, Carlos Agudo‐Blanco, Sergio Ramírez‐Barroso, Cristina Navío, Luis Bañares, Roger Bresolí‐Obach, Santi Nonell, Nazario Martín, David García‐Fresnadillo   +8 more
wiley   +1 more source

Unexplained syncope: what time-to-diagnosis and risk profiles tell us. [PDF]

Korean J Intern Med
Park YJ.
europepmc   +1 more source

Magnetic‐Driven Viscous Mechanisms in Ultra‐Soft Magnetorheological Elastomers Offer History‐Dependent Actuation with Reprogrammability Options

Advanced Science, EarlyView.
Magnetically induced microstructural rearrangements in ultra‐soft magnetorheological elastomers modulate their viscoelasticity, enabling programmable mechanical memory. Magnetic actuation induces long‐term viscous relaxation and double‐bumping stress responses due to particle chain formation.
Ernesto Gonzalez‐Saiz, Maria Luisa Lopez‐Donaire, Lucía Gutiérrez, Kostas Danas, Daniel Garcia‐Gonzalez   +4 more
wiley   +1 more source

Harnessing Dye-Induced Local Heating in Lipid Membranes: A Path to Near-Infrared Light-Modulated Artificial Synaptic Vesicles. [PDF]

ACS Nano
Sarker SR, Yamazaki T, Sou K, Takemura I, Kurita Y, Nomura K, Ichimura M, Suzuki T, Kai A, Araki T, Hattori S, Furuyama T, Chang YT, Kiya T, Arai S.   +14 more
europepmc   +1 more source

Low‐Temperature Annealing Triggered Abnormal Strengthening in a Complex Concentration Alloy via Evolutive Short‐Range Ordering

Advanced Science, EarlyView.
Low‐temperature annealing enhances strength, ductility, and work hardening in CoNiV MEA. This originates from multi‐scale chemical short‐range orderings (SROs) formed during annealing, which promote dislocation slip planarity and reduce entanglement, enabling balanced mechanical properties through ordering strengthening.
Yihan Wang, Yuan Wu, Yong Yu, Yang He, Xinyang Yu, Xiongjun Liu, Hui Wang, Suihe Jiang, Xiaobin Zhang, Zhaoping Lu   +9 more
wiley   +1 more source

Preoperative fasting in noncardiac surgery in a tertiary pediatric center applying European guidelines: the difficulty of giving drink to the thirsty. [PDF]

J Anesth Analg Crit Care
Ricci Z, Colosimo D, Donati F, Saccarelli L, Pizzo M, Schirru E, Giacalone S, Serio P.   +7 more
europepmc   +1 more source