Journal of Hematology & Oncology, 2020 Background Acute myeloid leukemia (AML) is the most common type of adult leukemia. Several studies have demonstrated that oncogenesis in AML is enhanced by kinase signaling pathways such as Src family kinases (SFK) including Src and Lyn, spleen tyrosine ...
Ola A. Elgamal +17 more
doaj +3 more sources
AZP-531, an unacylated ghrelin analog, improves food-related behavior in patients with Prader-Willi syndrome: A randomized placebo-controlled trial. [PDF]
PLoS ONE, 2018 Prader-Willi syndrome (PWS) is characterized by early-onset hyperphagia and increased circulating levels of the orexigenic Acylated Ghrelin (AG) hormone with a relative deficit of Unacylated Ghrelin (UAG).
Soraya Allas +14 more
doaj +4 more sources
The BTK Inhibitor ARQ 531 Targets Ibrutinib-Resistant CLL and Richter Transformation
Cancer Discovery, 2018 Targeted inhibition of Bruton tyrosine kinase (BTK) with the irreversible inhibitor ibrutinib has improved outcomes for patients with hematologic malignancies, including chronic lymphocytic leukemia (CLL).
Sean Reiff +2 more
exaly +2 more sources
Compact iodine-stabilized laser operating at 531 nm with stability at the 10(-12) level and using a coin-sized laser module. [PDF]
Optics Express, 2015 We demonstrate a compact iodine-stabilized laser operating at 531 nm using a coin-sized light source consisting of a 1062-nm distributed-feedback diode laser and a frequency-doubling element.
Takumi Kobayashi +8 more
semanticscholar +3 more sources
Search for the 531-day-period wobble signal in the polar motion based on EEMD [PDF]
Nonlinear Processes in Geophysics, 2015 In this study, we use a nonlinear and non-stationary time series analysis method, the ensemble empirical mode decomposition method (EEMD), to analyze the polar motion (PM) time series (EOP C04 series from 1962 to 2013) to find a 531-day-period wobble ...
H. Ding, W. Shen
doaj +2 more sources
Endoparasites of European hedgehogs (Erinaceus europaeus) in Germany and their zoonotic potential: proposed Capillaria ovoreticulata genetically identified as Capillaria putorii [PDF]
Parasites & VectorsBackground European hedgehogs (Erinaceus europaeus) are frequently infected with a variety of endoparasites. The hedgehogs’ synanthropic lifestyle results in frequent contact with pets and humans, posing the risk of parasite spillover from a One Health ...
Karolin Schütte +6 more
doaj +2 more sources
Enhancing Enantiomeric Separation with Strain: The Case of Serine on Cu(531)
Journal of the American Chemical Society, 2017 Yonghui Wang +2 more
exaly +2 more sources
AMG 531, a Thrombopoiesis-Stimulating Protein, for Chronic ITP
New England Journal of Medicine, 2006 James B Bussel +2 more
exaly +2 more sources
Future Oncology, 2022 Selpercatinib is a first-in-class, highly selective and potent, central nervous system-active RET kinase inhibitor. In the phase I/II trial, selpercatinib demonstrated clinically meaningful antitumor activity with manageable toxicity in heavily pre ...
L. Wirth +11 more
semanticscholar +1 more source
Study on the Effect of Ultraviolet Absorber UV-531 on the Performance of SBS-Modified Asphalt
Materials, 2022 Asphalt pavements at high altitudes are susceptible to aging and disease under prolonged action of UV light. To improve their anti-ultraviolet aging performance, UV-531/SBS-modified asphalts with UV-531 dopings of 0.4%, 0.7%, and 1.0% were prepared by ...
Li Liu +5 more
semanticscholar +1 more source