Results 181 to 190 of about 220,062 (240)

Multi‐omics–driven precision medicine

iMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li, Zhe Zhao, Yifan Zhang, Yao Ma, Gaofei Hu, Min Zeng, Zhanqun Yang, Zixuan Zhao, Xin Zhou, Wei Hu, Yuxuan Sun, Meng Su, Jun Li, Matthew Whiteman, Wei Fu, Chao Zhong, Lemin Zheng, Long Chen, Hairong Lv, Rongsheng Zhao, Yi Zhun Zhu   +20 more
wiley   +1 more source

Deciphering transcriptome complexity via long‐read sequencing

iMeta, EarlyView.
Long‐read sequencing is transforming transcriptomics from gene‐level quantification to isoform‐resolved interpretation by directly resolving full‐length transcript structures, transcription in repetitive regions, and linked molecular features. This review provides an end‐to‐end roadmap covering sequencing platforms, library preparation strategies ...
Chuwen Xu, Jia Li, Chenxi Yin, Keying Li, Tian Wang, Shiwen Gao, Yue Yu, Cheng Chang, Ye Wang, Guoqing Tong, Liang Gong, Wen Hu, Guoliang Chai, Yilai Han, Qian Qin, Suoqin Jin, Xiufen Zou, Bo Li, Tianyuan Zhang, Ana Conesa, Yunhao Wang, Dingjie Wang   +21 more
wiley   +1 more source

Discordant Antitumor Efficacy with Compromised Survival in High-Risk Unresectable Hepatocellular Carcinoma. [PDF]

Cancers (Basel)
Seo YE, Bae CJ, Lee WJ, Chun SY, Yoon JS, Baek YH, Kang YW, Rou WS, Song JE, Jeong J, Hong YM, Hwang SY, Cho HC, Hong JP, Woo HY, Heo J, Lee YR, Park SY, Tak WY, Yoon JH, Cho SB.   +20 more
europepmc   +1 more source

Hypervision Proton Surgery: The Future Direction of Proton Therapy

iNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source

Prevalence of indications of alcohol and drug use among patients treated for injurious falls by Emergency Medical Services in the USA. [PDF]

Inj Prev
Itzkowitz NG, Burford KG, Crowe RP, Wang HE, Lo AX, Rundle AG.   +5 more
europepmc   +1 more source

Maize Yield, Water Productivity and Economic Analysis Under Different Irrigation and Nitrogen Management Strategies Using Field Data and CERES‐Maize Model

Irrigation and Drainage, EarlyView.
ABSTRACT There is limited integrated evaluation of nitrogen (N) and irrigation management strategies for improving maize yield and productivity using crop models. The effects of N and irrigation on maize yield and productivity under centre pivot (CPI) and subsurface drip irrigation (SDI) using the CERES‐Maize model were investigated. N treatments were (
Ebrahim Amiri, Suat Irmak, P. Aalaee Bazkiaee   +2 more
wiley   +1 more source

Reprogramming a Hgt-family Kluyveromyces marxianus sugar transporter by site-directed mutagenesis to enable co-consumption of glucose and xylose. [PDF]

FEMS Yeast Res
Donzella L, Belloch-Molina C, Morrissey JP, Sousa MJ.   +3 more
europepmc   +1 more source

Performative Blame Avoidance

Journal of Applied Philosophy, EarlyView.
ABSTRACT Sometimes we avoid or minimize criticism for our failings by performing a merely symbolic act aimed at addressing a real or perceived blame allegation. Consider individuals or institutions performing land acknowledgements as a means of box‐ticking inclusion without committing to any significant change. Or consider corporations forming advisory
Nicolas Nicola
wiley   +1 more source

Correction to 'Behavioural clusters characteristic of cardiovascular reactivity profiles relate to poorer health outcomes'. [PDF]

Br J Health Psychol
europepmc   +1 more source

Association of tumor locations, clinical manifestations, and histopathological grade in meningioma: a 10-year single-center study. [PDF]

Front Oncol
Aninditha T, Tandian D, Andriani R, Sofyan HR, Savitri I, Harsono AR, Odilo J.   +6 more
europepmc   +1 more source