Results 61 to 70 of about 140,872 (266)

Functional anatomy, jaw mechanisms, and feeding behavior of Dunkleosteus terrelli (Placodermi, Arthrodira)

open access: yesThe Anatomical Record, EarlyView.
A new musculoskeletal reconstruction and revision of the cranio‐mandibular anatomy of the Devonian arthrodire placoderm Dunkleosteus terrelli from a comparative and functional anatomical perspective. Dunkleosteus is a specialized arthrodire with many specializations for feeding on large vertebrates, and many of its features are part of broader ...
Russell K. Engelman   +4 more
wiley   +1 more source

Periportal and Puncture Capsulotomy Techniques Have Similar Outcomes to Traditional Capsulotomies With Closure in Hip Arthroscopy: A Systematic Review and Meta‐analysis of 2‐Year Outcomes

open access: yesArthroscopy, EarlyView.
Purpose To systematically evaluate capsulotomy techniques through patient‐reported outcome measures, rates of revision arthroscopy, conversion to total hip arthroplasty, and achievement of clinically meaningful outcomes. Methods PubMed, Scopus, and Embase databases were queried in June 2024 for studies that could be used to compare capsular management ...
Brandon J. Allen   +9 more
wiley   +1 more source

Expression of codon optimized genes in microbial systems: current industrial applications and perspectives.

open access: yesFrontiers in Microbiology, 2014
The efficient production of functional proteins in heterologous hosts is one of the major bases of modern biotechnology. Unfortunately, many genes are difficult to express outside their original context.
Claudia eElena   +4 more
doaj   +1 more source

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva   +8 more
wiley   +1 more source

Investigation of Electrolyte Salts in Non‐Flammable Triethyl Phosphate for Sodium‐Ion Batteries

open access: yesBatteries &Supercaps, Volume 8, Issue 3, March 2025.
This study evaluates five sodium electrolyte salts (NaBF₄, NaClO₄, NaDFOB, NaFSI, NaPF₆) in triethyl phosphate (TEP) for sodium‐ion full‐cells, focusing on their physicochemical properties, solvation structure, and electrochemical performance. The addition of 1 wt.% vinylene carbonate (VC) improves cycling performance, with NaFSI demonstrating 88 ...
Wessel W. A. Van Ekeren   +4 more
wiley   +1 more source

GhWRKY75 positively regulates GhPR6-5b via binding to a W-box TTGAC (C/T) to orchestrate cotton resistance to Verticillium dahliae

open access: yesJournal of Integrative Agriculture
Verticillium dahliae is an important fungal pathogen affecting cotton yield and quality. Therefore, the mining of V. dahlia-resistance genes is urgently needed. Proteases and protease inhibitors play crucial roles in plant defense responses. However, the
Qichao Chai   +10 more
doaj   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher   +7 more
wiley   +1 more source

Energy trading using blockchain: Smart contracts functionalities – A systematic review

open access: yesEnergy Strategy Reviews
The widespread adoption of distributed energy resources poses challenges to the operation and management of electricity grids. The intrinsic characteristics of such resources, such as variability and dispatchability, require increased flexibility in ...
Santos L, Gomes A, Rupino P
doaj   +1 more source

Hypersensitivity Reactions in Serious Adverse Events Reported for Paracetamol in the EudraVigilance Database, 2007–2018

open access: yesPharmacy, 2019
Paracetamol is a popular and easily available drug which is used world-wide as analgesic, antipyretic agent. Hypersensitivity reactions to this drug involve a wide range of symptoms of various importance for patient management.
Iwona Popiołek   +2 more
doaj   +1 more source

Pharmacokinetic profiling of imatinib in relation to CYP3A4 activity in leukaemia patients

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Imatinib pharmacokinetics exhibit large interindividual variability because of differences in CYP3A4 activity—the main imatinib‐metabolizing enzyme. While therapeutic drug monitoring is effective, it requires steady‐state conditions and frequent sampling.
Anna Sofie Buhl Rasmussen   +14 more
wiley   +1 more source

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