Results 271 to 280 of about 2,314,355 (337)

From amides to thioamides: understanding enhanced anion binding in acyclic receptors. [PDF]

RSC Adv
Akhtar N, Lekanne Deprez S, Jayawardana SG, Davis M, Fonseca Guerra C, García-López V.   +5 more
europepmc   +1 more source

Proteogenomic Characterization Reveals Subtype‐Specific Therapeutic Potential for HER2‐Low Breast Cancer

Advanced Science, EarlyView.
Multiomic profiling of HER2‐low breast cancer identifies three proteomic subtypes with distinct therapeutic strategies: endocrine, antiangiogenic, and anti‐HER2 therapies. Genomic and lactate modification landscapes are detailed, providing insights for precise management.
Shouping Xu, Keda Yu, Lei Liu, Qin Wang, Xiaohui Wu, Yihai Chen, Guozheng Li, Xin Zhang, Bo Wei, Zitong Fu, Abiyasi Nanding, Zuxianglan Zhao, Lingbing Yang, Xingda Zhang, Jianyu Wang, Wantong Sun, Yi Hao, Zhongyi Cheng, Xiaojiang Cui, Hao Wu, Da Pang   +20 more
wiley   +1 more source

Magnetically‐Induced Suppression of Oxidative Stress Prevents Venous Thrombosis

Advanced Science, EarlyView.
Venous thromboembolism (VTE) remains a leading cause of cardiovascular mortality. This study demonstrates that static magnetic fields (SMF) offer a novel non‐pharmacological intervention against VTE by mitigating endothelial oxidative stress. Mechanistically, SMF elevates intracellular Ca2+, boosts ATP production, and suppresses NOX4‐mediated ROS ...
Nana Zhang, Yirong An, Shiran Tao, Shenao Qu, Minge Wu, Guantong Fang, Ziqing Chen, Weilun Song, Haoze Leng, Rongqian Wu, Yi Lyu, Xiaoli Liu, Dinghui Dong   +12 more
wiley   +1 more source

Shared requirement for MYC upstream super-enhancer region in tissue regeneration and cancer. [PDF]

Life Sci Alliance
Sur I, Zhao W, Zhang J, Kling Pilström M, Webb AT, Cheng H, Ristimäki A, Katajisto P, Enge M, Rannikmae H, de la Roche M, Taipale J.   +11 more
europepmc   +1 more source

Initial Distance‐Dependent Mean Force Drives Synaptic Vesicle Motion Toward Fusion Sites in Stimulated Hippocampal Neurons

Advanced Science, EarlyView.
Synaptic vesicle (SV) motion and exocytosis dynamics in the presynaptic terminals of live neurons are intimately linked to synaptic transmission during neuronal activity. In this work, it is revealed that, during electrical stimulation, SVs located farther from their fusion sites exhibit greater straightness and experience larger mean forces directed ...
Gyunam Park, Ji‐Hyun Kim, Hunki Lee, Chungwon Park, Sidong Chen, Luke Bates, Jaeyoung Sung, Hyokeun Park   +7 more
wiley   +1 more source

Development and validation of a high-density 'Amahysnp' genotyping array in grain amaranth (Amaranthus hypochondriacus). [PDF]

BMC Plant Biol
Singh R, Mahato AK, Rajkumar S, Singh AK, Singh A, Maurya A, Gupta R, Bhardwaj R, Kaushik SK, Kumar S, Gupta V, Singh K, Singh GP.   +12 more
europepmc   +1 more source

Targeted 2‐Deoxy‐D‐Ribose Delivery by Biomimetic Nanoplatform Activates EGFR for Accelerated Heart Valve Endothelialization

Advanced Science, EarlyView.
This study develops a biomimetic nanoplatform using erythrocyte membrane‐camouflaged, CD144 antibody‐functionalized nanoparticles to deliver 2‐deoxy‐D‐ribose (2dDR). This system promotes heart valve endothelialization by enhancing endothelial cell migration and proliferation via EGFR activation, while improving hemocompatibility.
Xiang Qiu, Gaofeng Li, Wenyi Wan, Jinsheng Li, Ge Yan, Shijie Wang, Xiuqi Hu, Zongqi Han, Yazheng Shan, Ying Zhou, Nianguo Dong, Weihua Qiao   +11 more
wiley   +1 more source

Deciphering drought tolerance in cotton genotypes through integrated morpho-physiological and biochemical markers at flowering stage. [PDF]

Sci Rep
Shani MY, Ditta A, Khan MKR, Rahimi M.
europepmc   +1 more source

Zinc-Mediated Loading and Release of His-Tagged Recombinant Proteins in Self-Assembling Peptide Coacervates. [PDF]

ACS Appl Bio Mater
Clegg B, Reddy GA, Velankar KY, Ostrowski SM, Liu W, Fan Y, Gawalt ES, Meng WS.   +7 more
europepmc   +1 more source